I have Reiter's and I've been on NSAIDs for a year. I know that Amyloidosis can cause PN. I know that Amyloidosis is caused by a chronic infection or inflammation. My Rheumatologists say I don't have inflammation. So I'm wondering if tooth decay, masked by painkilling NSAIDs, could be a cause of Amyloidosis and thus my PN ?
Many thanks, Ken
Good logic, but most unlikely!
Amyloidosis from chronic inflammation (such as from osteomyelitis, soft tissue abscesses, rheumatoid arthritis, etc) generally affects some of the internal organs (such as the kidneys) rather than the nerves. Nerves are more likely to affected with primary amyloidosis, familial amyloidosis, or amyloidosis related to some specific malignancies (plasma cell related).
Unless you have the worst tooth decay there can be, it is unlikely that you have secondary amyloidosis from the tooth decay.
I hope you find this reasuring.
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