Thanks for using the forum. I am happy to address your questions, and my answer will be based on the information you provided here. Please make sure you recognize that this forum is for educational purposes only, and it does not substitute for a formal office visit with a doctor.
Without the ability to examine and obtain a history, I can not tell you what the exact cause of the symptoms is. However I will try to provide you with some useful information.
Paroxysmal nonkinesigenic dyskinesia (PNKD) is a movement disorder characterized by daily to monthly attacks lasting anywhere from a few minutes to hours. The triggers are not action based but rather by alcohol, caffeine, fatigue, or even stress. The disorder has been shown to have a genetic basis. The difficulty with this disorder is the lack of response to typical medications such as the anticonvulsants (which are sometimes used for movement disorders and other neurological disorders). Other options may include a benzodiazepine, acetazolamide, or even a neuroleptic.
Regarding your brain MRI: There are multiple causes for so called plaques (or hyperintensities as you describe) in the brain. Most often, these are due to what is called "chronic small vessel disease", literally meaning diseased small vessels that supply blood flow to the brain. This is not an uncommon process in the brain and increases with age. This is not a disease in and of itself but rather is a reflection of unhealthy blood vessels, damaged by years of plaque build-up. This is most often due to a combination of several factors including the following: high blood pressure, diabetes, smoking, and high cholesterol. If these factors are well controlled, the damage to the brain can be stabilized and further damage prevented.
Other causes of plaques in the brain can be migraine. People with migraine often have plaques on their MRI that are of unclear cause or significance.
Other causes of plaques on MRI can usually be distinguished based on history and symptoms, such as symptoms of neurologic deficit (for example arm weakness or difficulty walking etc). These can also be distinguished based on the MRI appearance. These include, but are not limited to, multiple sclerosis, other demyelinating disease, and inflammatory processes such as vasculitis.
I would recommend that you continue following up with your movement disorder specialist. You do have a complicated presentation that does sound like it will require a specialist as you are doing.
Thank you for this opportunity to answer your questions, I hope you find the information I have provided useful, good luck.
I am sorry if I am putting in too much info. I just desperately want help.
The uncontrollable body movements have become and everyday thing. It is ruining my life. I am in constant pain, getting depressed and my daughter is scared to come around me because I look so odd. I hope this doesn't overload you but I thought by getting it all out at once it may make a difference.
Thank you very much.
I just wanted to add the day to day other problems.
Having trouble peeing and severe constipation
I am now having rashes. Also have two spots on my spine that are very sensitive. The numbness in my right big toe, hand, arm and leg are getting worse.
1. My fingers lock into place and i have to manually move them, neck, middle and lower back are constantly hurting, perfuse sweating, nervousness, feeling like I have low blood sugar but when tested its fine, shaking, short term memory problems, stuttering, concentration problems.
2. I year ago when in hospital I couldn't open my hand, move my wrist, little to no reflexes, sweating, vomiting, weak muscle control, no reaction to rubbing of sharp objects on legs, arms, feet, eyes moving rapidly with double vision, anxiety, short term memory problems, stuttering badly, concentration problems, hands and feet numb
3. Uncontrollable body movements, facial grimacing, vomiting, hands and feet numb, eyes moving rapidly with double vision, anxiety, stuttering badly, short term memory problems, concentration problems, sweating. All symptoms were made better when I took Valium. This lasted for about 3 weeks. It started out gradual then increased to everyday. It was not so bad in the morning but became very bad at night. When I ate it made everything worse and caused me to throw up.
I am now on 2 10mg of Valium, 3 20mg of Baclofen and 3 mg of Klonopin a day.