I have been on Topamax since Feb., I have very slowly worked up to 100mg. The side effects have been tolerable but I went from 25 to 50 very quick and the side effect were bad: Brain fog, no appetite, tingling, insomnia. I went from 50 to 75mg, 5 weeks later and 75 to 100mg 4 weeks later, working up slowly does help with the side effects. Over time I have found most of my side effects subside: I take it for nerve pain and complex migraines. I did experience weight loss but not loss so far, but I do take daily vitamin and extra supplements plus making sure I drink Ensure and a V-8 everyday to keep myself health. I didn’t need to lose any weight. I also cut all alcohol out with the exception of the occasional glass of wine with we are out to dinner with friends…. (Mostly so I don’t look like a party pooper) and anything carbonated taste awful. I still had 13 migraines last month, so the neurologist is still trying to get me on the correct dose. But I also have two lesions on my brain from my migraines so what’s one more…..LOL
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