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ischemic microangiopathy
I recently received the result of my MRI.  I have been dizzy but mostly have a very uncomfortable "weird" feeling in my head that makes it hard to think clearly at times.  

MRI IMPRESSION:  Nonspecific high signal changes in the white matter bilaterally, may be in keeping with ischemic microangiopathy.  No abnormality of the IACs.  the cervical spine is normal.

Do you have any idea what this means?
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1093617 tn?1279305602
There can be several possibilities in your case but without being able to clinically correlate your MRI reports, I can not be precise on diagnosis.  Your report suggests ischemic changes that involve the brain white matter, either exclusively or in combination with grey matter changes. This may occur due to metabolism errors, exogenous toxins released by virus, autoimmune disease, leukodystrophy, demyelination, and radiation effects. Spasticity, muscle weakness, paralysis, hyper-reflexia and movement disorder may be the clinical features associated with white matter disease that need to be evaluated thoroughly. However, it is sad to say that there is no permanent cure but conservative treatment & physiotherapy exercises that would help you to regain your normal function and stopping the further progression of the disease. Please consult a neurologist in this regards. Hope this helps.

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Thank you for your reply.  

Would you please explain what these the MRI FINDINGS mean?

MRI FINDINGS:  Scattered areas of high signal foci are present in the white matter bilaterally primarily involving periventricular white matter as well as the corona radiata and centrum semiovale.  These are nonspecific in nature.  There is no involvement of corpus callosum.  No space occupying lesion or mass effect is demonstrated.  No structure abnormality is evident.  There is no evidence of high signal on the diffusion weighted sequence to suggest acute ischemic or infarotion.

The IACs are normal and symmetric in appearance.  

Cervical vertebral body alignment is satisfactory.  The cervical intervertebral discs are maintained and there is no evidence of central spinal canal stenosis or neural foraminal compromise.  Signal intensity of the spinal cord from craniocervical junction to the T4 vertebral body level is normal.
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1093617 tn?1279305602
Although your reports suggests that your brain white matter have ischemic microangiopathic changes, but without being able to placing your finding into clinical correlation I can not be precise in the diagnosis. Apart from this finding, rest of your report seems normal. I would suggest consulting a neurologist in this regards. Hope this helps.
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My mum too has the same as you with the constant weird feeling in her head she is due to start physio next week do you think this will get rid of that feeling (like her head wants to explode) or could you give me any tips to help her please. Tess
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My mri reports also states small vessel ischemic change. I am not able control my emotions, reaction (facial), hard to think clearly, communication disorder. What can i do futher to improve myself?
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I also need help understanding my MRI impressions.
"Punctate foci of signal abnormality left frontal lobe, a nonspecific finding. This could relate to microangiopathic ischemic disease. Clinical correlation recommended."  "There are punctate foci of increased signal on long TR sequences in the left frontal lobe." " There is prominent Virchow-Robin space inferior to the left basal ganglia."Does this mean I should follow-up with a neurologist? Would this present any symptoms? Thanks for your help!!
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Findings are non specific but could indicate foci of on senescent ischemic microangiopathy, demyelination, or migraine related white matter disease.  Clinical correlation is suggested.  Gradient echo and diffusion scans are normal.  
IMPRESSION: Scattered foci of abnormal white matter signal intensity.  Differential considerations include senescent ischemic microangiopahy, demyelination, or white matter disease related to migrane headaches.  clinical correlation is suggested.
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