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Neurology (Expert Forum)
myotonic dystrophy and tegretol
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myotonic dystrophy and tegretol
by tom__0__0, Aug 27, 1998 12:00AM
I have a pt. c Myotonic Dystrophy. His two sibling daughters live back east and have been started on tegretol for this. I have no information on the use of tegretol for this condition, saw your web site do you know of any studies/ published on the use of tegretol and myotonis dystrophy. a PA in CA
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nothing has been published on this topic in the last 5 years , however I
have found a few isolated case reports of the use of Tegretol in the
treatment of myotonia in the 1970's and 80's. The drug has a menbrane
stabilizine effect which reduces the sustained muscle contraction (myotonia )
which is a feature of the disorder. It is indicated if this symptom is not
prominent.
I have attached a reference which you may find useful.
Sechi GP. Traccis S. Durelli L. Monaco F. Mutani R.
Carbamazepine versus diphenylhydantoin in the treatment of myotonia.
European Neurology. 22(2):113-8, 1983.
