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neuropathy please help me

neuropathy please help me

Well i noticed a buning like sensation in my left pinky toe some 5 WEEKS post possible exposure, at first than it disappeared and had moved up to the back of the leg near the Peroneal nerve AREA or below calf muscle, like the back of the leg where the shin is...Only on the left leg, and it was on and off very intermittent

NOW some 6-7 days later the burning sensation is completly gone, not present and its almost 7 week will go for another test

I earlier tested NEGATIVE for both HIV RNA and Antibody on the 26th day from my (possible excposure)scare, These tests are they capable enough to pick up the virus IF I WAS INFECTED??  How reliable are they!!

Biorad 3rd gen Igm and IgG: Antibody test

GenProbe APTIMA HIV-1 qualitative assay. Sensitivity of the assay is 30 copies/mL (98.5%) and 100 copies/mL (100%). :RNA TEST

what do you think Doctor does it sound like AIDP which is seen in primary hiv or rare mononuretis multiplex or mononeurapthy
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Avatar_dr_f_tn
Hi there. The most common type of neuropathy in HIV is a distal painful sensorimotor polyneuropathy but it usually develops during late HIV infection. It is rare in otherwise healthy seropositive patients. HIV associated distal painful peripheral neuropathy is a progressive disease unless secondary causes like vitamin deficiencies and neurotoxic drugs can be eliminated. The other causes, which need serious thought, are acute inflammatory demyelinating polyradiculoneuropathy, diabetic neuropathy, HIV associated multiple mononeuropathies, nutritional and B12 associated neurological disease, etc. there are other HIV related neuropathies.
Diagnosis of HIV involves serum HIV antibody by ELISA confirmed by western blot.  Antibody might be negative if it is a recent infection, window period 1-3 weeks after exposure. In this scenario,HIV RNA (PCR) or core p24 antigen in plasma or ELISA repeated at 6 weeks and 3 months can be done. You need to confirm positive results of rapid tests by western blot.
the peripheral neuropathy work up would include HIV RNA viral load, CBC, FBS, HbA1C, ANA screen, ESR, renal function test, lyme serology, paraproteinemia workup, thyroid function test, hepatitis workup, B12 and folic acid levels, cerebrospinal fluid analysis and electromyography. You would need a neurologist to help you with these concerns. Hope this helps. Take care.
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