polio vs parkinsons

[daughterwithquestions]

my mother had polio as a child, now at 76 she is experiencing symptoms of parkinsons,
she has been on wellbutrin for about 8 years.
I am a family Nurse Practitioner, so feel lost, No one weems to be looking at this as a whole.
Where do I begin.
She has had MRI which was negative
She was started on Sinemet but her falls have increased- this past week she feel and hit her head, he falls are presenting quit differently from previous falls.
Please help with suggestions.

[DrNavneetMD]

Dear,

Carbidopa is dopa decarboxylase inhibitors. They help to prevent the metabolism of L-dopa before it reaches the dopaminergic neurons and are generally given as combination preparations of carbidopa/levodopa (e.g. Sinemet) There are also controlled release versions of Sinemet that spread out the effect of the L-dopa. Duodopa is a combination of levodopa and carbidopa, dispersed as a viscous gel. Entacapone inhibits the COMT enzyme, thereby prolonging the effects of L-dopa, and so has been used to complement L-dopa.
The dopamine-agonists bromocriptine, pergolide, pramipexole, ropinirole , cabergoline, apomorphine, and lisuride, are moderately effective.
Selegiline and rasagiline reduce the symptoms by inhibiting monoamine oxidase-B (MAO-B), which inhibits the breakdown of dopamine secreted by the dopaminergic neurons.

Best

[daughterwithquestions]

How can you differentiate between post polio , parkinsons and parkinsons iduced by use of wellbutrin?