Help. I have severe anterior thigh pain through out the day, but more pronounced at night preventing sleep. The pain can be in one thigh or both thighs. It is awful. I am in perimenopause and have uterine fibroids. Is it possible a fibroid could be impinging on a nerve causing this pain as it does get worse when I lay down? Please help. I have had this problem for over two years. Multiple tests, bone scan, MRI of back, tons of labs. All come back fine. This is not in my head.