whats the alternative?

My Bf was diagnosed with a gemistocytic astrocytoma grade 2,in 2008 he had 75 percent ressection of the tumor which is located in his right parietal lobe...36 treatments of radiation...which seemed to do no good he was then put on temodar...3 month mri after the chemo showed no new enhancement so he was left on chemo and mri scheduled for 6 months later....Mri yesterday showd slight enhancement increase in tumor bed area...whats next if the temodar is no longer working? Is there different chemo meds he can try?

[Dr. A. Srivastava]

Hi, Thank you for your question. Generally, grade-2 astrocytoma is slow growing and represents with most common symptoms of seizures. Although resection along with radiation & chemotherapy of tumor may provide relief in symptoms (seizures) in one or to years, but due to invasive nature of the tumor it may recur as well. Therefore, your treating doctor will be in best position to let you know the precise outcome after the surgery. Hope this helps.