Glutamate Modulating Therapies

Hey everyone,

I have tried many different ocd drug therapies, but have yet to try a glutamate modulating therapy such as Memantine (Namenda), Riluzole (Rilutek), N-acetyl cysteine, or amantadine. If anyone has information on or experience with any of the above medications, would you please share that with me? I am desperate.

Thanks so much.

[JGF25]

I'm sorry to say that I don't know much about these medications.  There is quite a bit of literature, some old and some new, out there.  You have obviously been on other medications so were you seeing a psychiatrist?  What does he/she say about these medications?  It looks as if there has been some efficacy but everyone is different so it is hard to say whether these would work any better than the SSRIs for instance.  

To be honest with you I take Wellbutrin which is not the first line drug for OCD but it works for me so everyone is different.

You might try posting on the Anxiety forum where there is more activity at the moment to see if anyone has tried these medications for anxiety.  

Sorry if this is of absolutely no help to you.