My son has been on Letrozole for a year to stop his bone plates from fusing. Last year his bone age came in at that of a 14yr old. We were told that the letrozole would stop the progression. Just went for another bone age and it came back at almost 15. What do we do? I am upset beyond words! What do you think our options are?
Well, without knowing the relevant clinical details such as the indication for using letrozole/ delaying growth plate fusion, it would be difficult to comment specifically on the situation. Letrozole would not prevent and would just cause a delay on growth plate fusion, while the effect on the final height is still a controversial topic. Age determination by radiographs/ bone age is not dot specific and always has a range on +/-1-2 years, so a bone age of 15 at the age of 13.5 may not be something to worry about. I would suggest discussing the situation in detail with his treating doctor.
Hope this is helpful.
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