Ovarian Cancer Expert Forum
5th Line Chemo
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5th Line Chemo

1st line 6 cycles iv taxol + carbo & 3 cycles IP cisplatin consolidation (1 Year Remission)

2d line 6 cycles iv carboplatin + Doxil ( No surgery) and PET/CT at end of treatment showed No Evidence of Disease ( 1 Year Remission)

3d line Gemzar + Avastin + Oxaliplatin (no surgery) and PET/CT at end of treatment showed No Evidence of Active Disease 7 month treatment free interval.

4th line 12 weekly taxol CA125  which came in at 8.5 at end of treatment.  10 months treatment free interval.  Though CA started to rise just after the treatment onc did not want to do anything until she developed some symptoms.

Her latest CA125 is 500.  She has massive Pleural effusion in her right lung which has made it collapse.  PET scan shows metastasis to her right pleural space.

She had her Pleural tap yesterday (3 ltr fluid removed) and her lung has expanded back.  Oncologist is looking into 3 options.  What is your opinion on this?

(1) Trabectedin:  I do not see much data on this and it does not seem to be more effective thatn the other options and has a lot of side effects and is very expensive
(2) Weekly Topotecan
(3) Weekly Carboplatin

Thank you
1 Comment
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Dr Goodman,  Mom's plural drain dropped to 75 ML today so her oncologist performed Pleurodesis using Bleomycin.

He is going to start her on a 21 day cycle of Carboplatin.  She will receive her 1st cycle tomorrow and then be discharged.
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