I am writing to see if anyone can give me more information on Abraxane use in Ovarian Cancer--I have seen some old posts from 2005 on here, but nothing more recent.
My mother is 56 and was diagnosed with Stage IIIc in 2005--debulking/staging surgery and 6 cycles of chemo (taxol), but now has a recurrence of her disease. We are devastated as anyone may imagine--life just keeps throwing us challenges we don't need. If you have any information or can direct me to any information that would be truly appreciated.
Abraxane has a website abraxane.com. I am not familiar with it. The last ovarian use I could find was a phase 2 trial around July 07. It is taxol plus a human blood protein albumin. The drip was 30 minutes compared to 3 hrs. for taxol. Is this what the dr. has decided to use? Will it be combined with another chemo? I am 54 and am on chemo for recurrence. Abraxane does not seem to be one of the group used on recurrence is why I ask. It is usually a repeat of the original drugsif there has been a 6 month to a year remission. Other common ones are doxil, gemzar,taxotere. topotecan, and avastin.
It belongs to taxol family and it has been proved for breast cancer, it is in trail for OVCA. U can find more info on the web as msjazz mentioned. I just want to add since albumin is a human protein already, it will not need premedication as taxol does,30min compare to 3 hrs, and grade4 neuropathy is much less that using taxol. I have used Abraxane for consolidation chemo. So far so good and one more to go. Best wish for your mom.
The other 2 have told you about as much as I know of abraxane too. It is a reformation of the drug taxol. And yes it takes about 30 min to recieve via IV drip. I am currently on Avastin/ Abraxane myself. It has a few of the same side effects as taxol, just not quite as harsh. I did start losing my hair and shaved it off but it did not come completely out like on taxol. It is very thin in places so I would have shaved it anyway, but it is already growning. But I do recieve premeds with it. Plus I take 2 tylenols and 1 compazine before hand. I hope that all goes well for your mom.
Hello there. I will be taking Abraxane as well. I don't know too much about it yet, but I will let you know once the drug is given. I'm not sure I will give the best advice because this drug is one of the 5 other chemo drugs given to me at the same time. Best of luck to your mom and keep us posted. With love, Deandra
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. MedHelp is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.