Arimidex and recurrent ovarian cancer - any sucess or published information?

[moosiemae]

Is there any clinical published information about success with the use of Arimidex in a patient with advanced ovarian cancer?

I had one clinical trial so called "Triplet Doublet" two years ago and, and in FEb of 2006, I finished 9 cycles of Gemzar and carboplatin. Disease appears stable now but CA 125 has risen slightly. I expect to be in treatment soon within a few months.

MDs just started me on Airmidex. Any info about any success with Arimidex would be appreciated as well as any infor on bothersome side effects and do these side effects lessen?
I was already on Tamxoxifen  sevral years ago after treatment for breast cancer and recall the hot flashes....

Thanks!

[jappraxin]

I have been fighting ovarian cancer since '94 with a 12 year remission until 2006. It metastized to my lymph nodes and I was initially treated w/Cisplatin, Ectopiside, and Bleomyicin successfully. In 2009, I was again put on Cisplatin and Ectopiside. My white cell count dropped to .5, uncontrollable vomiting and diarhea all put me in the hospital for two weeks.  They gave me several transfusions and tests and found another tumor on my lymph nodes. I was released and after 8 wks w/o chemo, they started me back on the same regime. My white cell count again plummited to .3. No hospital but they stopped that chemo via my port since then. I'm currently taking Arimidex. My neuropathy, joints, and pelvic pain have worsened. In fact it feels like nails r being hammered thru my finger nails! I want to know if there is any success w/using Arimidex for ovarian cancer, when it was primarily used for breast cancer. Thank u in advance for ur response.

[Anna-maria74]

One thing I found really hilarious was that my diazepam (valium) had written on the back 'may cause anxiety' work that one out!!!!!!!!!!

Anna x

[nic2006]

Sorry for all that info.  I just copied and pasted everything that was there on the subject; seems like the solutions are worse than the problems:)
Nicole

[moosiemae]

thanks. While rading all of that is very off-putting -on the other hand, if it can help me, I am willing to give it a try.
Thank you!

[nic2006]

Hello, I was just browsing the site and read your post.  Here is a little information on Arimidex.  More common side effects may include:
Abdominal pain, accidental injury, anxiety, arthritis, back pain, bone pain, breast pain, cataracts, chest pain, constipation, cough, depression, diarrhea, dizziness, dry mouth, flu-like symptoms, fractures, headache, heart disease, high blood pressure or cholesterol, hot flashes, infection, insomnia, joint disease or pain, loss of appetite, nausea, osteoporosis, pain, pelvic pain and stiffness, "pins and needles," rash, shortness of breath, sore throat, stomach and intestinal upset, sweating, swelling of arms and legs, urinary tract infection, vaginal discharge or inflammation, vomiting, weakness, weight gain.  Less common or rare side effects may include:
Blood clots, bronchitis, confusion, drowsiness, feeling of illness, fever, hair thinning, heart attack, increased appetite, itching, muscle pain, nasal or sinus inflammation, neck pain, nervousness, severe blisters in the mouth or other mucous membranes, sluggishness, stroke, temporary tumor growth, tense muscles, vaginal bleeding, vaginal dryness, weight loss

Hope this helps...still looking for clinical trials studies on this subject as well.
Nicole