Avastin and Cytoxan

Just started on Avastin and Cytoxan, and my CA went from 316 to 254 after one treatment.   My question is,  if the numbers continue to go down,  and I take a break from chemo.   On recurrence?   Can I go back on Avastin,  or is it just like the other drugs, Topotecan, doxil, gemzar,  that you need to change?

  Since Avastin is not a chemo,  can you just go back on?

[Annekathryn Goodman, M.D.]

hi There,

that is an interesting question. Our experience with avastin is very new. There are some who wonder if you need to just stay on avastin once you start it. As avastin works to reduce blood vessels, and not to kill the actual cancer, we worry the tumor could bounce back when the drug is stopped. But with time and experience, we will understand this better.
That is great that your CA 125 is dropping.
please keep us posted on how your are doing.
best wishes