I was diagnosed ovarian cancer stage IV, 3 years and half ago.
First surgery was only exploratory as they couldn't do anything. Then chemo: Cisplatinum+Taxol. Second surgery: optimal debulking. After it chemo again: another round of Cisplatinum+Taxol and then Taxol alone for maintenace. Then first recurrence: bowel obstruction. Third surgery: exploraty only as they found out massive peritoneal metastases (microscopic disease).Chemo took care of it: another round of Cisplatinum+Taxol. Then second recurrence: again bowel obstruction. Chemo took care of it once more: Caelix. Then Topotecan due to a rising CA125 while on Caelix. That's when liver metastases showed on CT. Now, what seems to be my third bowel obstruction but this time while on chemo, Avastin+Endoxan (it took care of my liver metastases and tumor next to the iliac artery, though). I've started new chemo: Carboplatin+Gemzar once every 3wks, 2nd cycle finishes wednesday, bowel obstruction still persits. Some good signs nevertheless: did feces twice, no vomiting. My abdomen is not distended. Last CA125=140 (before chemo's 2nd cycle) from 148.
I'm now starting to think that I might have some adhesions from my last surgery which are the cause of the bowel obstruction since my CA125 was around 600 for the other two recurrences and now is just 140. Moreover, my abdomen was "stiff" and I didn't have gas like have been having now, nor I ever felt the intestines moving like I do now. Nothing on CT & Xray.
What is your opinion: adhesion or cancer? Surgery or keep on chemo?
Thank you for the additional information. I would lean towards chemo. Another test that you can ask your doctor about is n upper GI series with small bowel follow through. sometimes this can give more information about your bowel and the narrowing beyond what you see on ct scan. of course, your doctor who has seen your actual films will know if that will add information
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