Ovarian Cancer Expert Forum
Carboplatin reaction, or not.
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Carboplatin reaction, or not.

My mum:
(Stage 3 diagnosed March 2005, debulk and carboplatin and taxol, remission until Nov 2007. CA125 in March 2005 512)
Mums oncologist has increased her carboplatin to 685 from 550(whatever chemo is measured in). As mum had a reaction 3 weeks ago to the carboplatin her oncologist this week wrote on the notes to increase the infusion time from 30mins to at least 2hrs. This wasn't done by the chemo nurses, they gave it to her over 30 mins and she reacted again this Friday to the carboplatin so she had steroids and antihistamines and the chemo Dr was called who reprogrammed the drip for 2 hours and she was fine.
Do you think the carboplatin is being administered to quickly?
I don't think she is allergic to carboplatin completely as surely she would react how ever fast or the slow it was being pumped in.

Also, mums CA125 was 60 in Nov 2007 when reoccurance was discovered, after the 1st chemo it dropped to 25, is this a good sign it is working, when she was ill the first time CA125 was 512?

Thanks
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242604_tn?1328124825
Hi There,
it sure sounds like she has developed an allergy to carbo. The next thing she needs to do is to see an allergist to confirm this.
let us know what happens
take care
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