Concerned with Diagnosis Large cell neuroendocrine carcinoma of ovary
After finding a mass on my right ovary, surgery was performed to have it removed. At the time it was positve for cancer, so they removed lymph nodes etc but left my uterus, because it appeared to be stage one and contained to that ovary only (and they considered me young 40). The pathology came back confused so my oncologist had slides recut and tested at another facility and reviewed by a tumor board. I have been diagnosed with large cell neuroendocrine carcinoma of the ovary. Because of its aggressive nature, we will be doing a full historectomy and then chemotherapy.
I have not found much info on this type of ovarian cancer. Are there recommended chemotherapy treatments, are there other conditions I/my primary care physician should be on the lookout for. I will be having another abdominal ct before the next surgery.
Any information or case histories you might be able to lead me to, would be appreciated.
I found one case history that I could get access to without a charge or subscription:
Kazem Behnam, David Kabus, and Melody Behnam
The Valley Hospital, Ridgewood, NJ 07450, USA
Background. Non-small cell neuroendocrine carcinoma (NSCNEC) of the ovary is a rare neoplasm, characteristically arising in association with a surface epithelial tumor.
Case. A 27-year-old woman with no significant past medical history presented with a 17-cm left ovarian tumor. She underwent an exploratory laparotomy with resection of the pelvic mass. A diagnosis of stage IA non-small cell neuroendocrine carcinoma was rendered. She was subsequently treated with Taxol and Carboplatinum
Due to the rarity of this neoplasm, a general consensus for optimal treatment has yet to emerge. Although the case described here was clinically a stage IA tumor, the reported biological aggressiveness of these tumors prompted treatment with chemotherapy. Additional cases of these tumors will have to be collected and studied to establish optimal therapeutic guidelines.
They did not indicate her prognosis or outcome.
also found this:
"patients, particularly those with stage I disease and/or those who have received platinum-based therapy, have a more favorable prognosis."
Sounds like your doctor is doing the appropriate treatment by advising chemo.
A gynocologic oncologist should be performing your next surgery.
I will keep you in my thoughts and prayers. Good luck.
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