Dxed stage IV one yr ago. After debulking and chemo ca125 dropped to 6, then 11, and has stayed at 4. Hip bone pain began several months ago yet ca125 hasn't risen. no other symptoms. no ascites, normal blood work. No chemo for 4 months. Is it possible to have bone mets with a normal ca125? An MRI is scheduled for the end of the month. Thank you!
I do not recall bone as a likely place for ovarian cancer to spread, but I suppose it is possible. It usually spreads across the abdomen and into the chest area (lungs.) Also, if the original ovca produced CA-125, then any recurrence should also produce it, should't it? It is the same cancer, and that is the reason the CA-125 level is checked - to determine recurrences.
Here is another possible scenario - a friend's brother had cancer and underwent chemotherapy. The treatment was successful; however, the steroids he was given to combat some of the side-effects of the chemotherapy caused his hip joints and cartilage to "erode." He finally had hip replacement surgery when it was obvious that he was a cancer survivor.
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