Ovarian Cancer Community
Gene therapy research by the U of Pittsburgh
About This Community:

This patient support community is for discussions relating to ovarian cancer, biopsy, chemotherapy, clinical trials, genetics, hysterectomy, immunotherapy, radiation therapy, screening, and staging.

Font Size:
A
A
A
Background:
Blank
Blank
Blank
Blank Blank

Gene therapy research by the U of Pittsburgh

Saw this today and thought...cool :) Obviouslly not in clinical trials yet

http://www.alanpeto.com/ovarian_cancer/blogs/38



Pitt Researchers: Gene Therapy Inhibits Ovarian Cancer Growth

Breakthrough May Improve Prognosis Of Deadly Cancer

POSTED: 2:52 pm EDT June 4, 2007
UPDATED: 5:06 pm EDT June 4, 2007

PITTSBURGH -- University Of Pittsburgh researchers have used gene therapy to either completely abolish or significantly inhibit tumor progression in a mouse model of ovarian cancer.

These findings were presented at the American Society of Gene Therapy annual meeting in Baltimore over the weekend.

Researchers believe this breakthrough may significantly improve the prognosis for ovarian cancer patients.

Ovarian cancer is diagnosed in more than 25,000 women in the United States each year, and about 16,000 American women die from the disease annually.

Despite aggressive surgery and chemotherapy approaches, the prognosis for ovarian cancer is poor, and most women have a life expectancy of only three to four years after their diagnoses.

The Pitt researchers found complete inhibition of tumor growth in the mice that were treated immediately with gene therapy and significant tumor inhibition in the 30- and 60-day delayed treatment mice.

In contrast, all non-gene-therapy treated mice either died or were euthanized due to overwhelming buildup of fluid in the peritoneal cavity by 94 days following tumor inoculation.

According to corresponding author David L. Bartlett, M.D., professor of surgery and chief of the division of surgical oncology at the University Of Pittsburgh School Of Medicine, gene therapy offers an attractive new approach for treating ovarian cancer.

According to Bartlett,
Related Discussions
1 Comment
Blank
Avatar_f_tn
Hi Alan... a friend of mine has just started gene therapy in Alabama. She is one of a selected few who passed the criteria. She had her first treatment last week, and is having it in conjunction with chemo via a couple of ports. I'll find out more as she goes along, but it's interesting... .another option for us,maybe.
Hope your Mum is doing well....hugs...Helen...
Blank
Continue discussion Blank
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
Ovarian Cancer Community Resources
RSS Expert Activity
233488_tn?1310696703
Blank
New Cannabis Article from NORTH Mag...
Jul 20 by John C Hagan III, MD, FACS, FAAOBlank
242532_tn?1269553979
Blank
3 Reasons Why You are Still Binge E...
Jul 14 by Roger Gould, M.D.Blank
242532_tn?1269553979
Blank
Emotional Eating: What Your Closet ...
Jul 09 by Roger Gould, M.D.Blank
Top Ovarian Cancer Answerers
667078_tn?1316004535
Blank
HVAC
Durham, NC