OVARIAN CANCER COMMUNITY
Incorrect CA-125 Test

Incorrect CA-125 Test

Has anyone had a false positive ca-125 test? My Mom's test went from mid twenties to 54. She had a cat scan was after her blood test and it was negative for cancer. We are wondering if the test could be incorrect. We know that infections can skew the results. She has a yeast infection and cold sore at the time of her last test. She was also was a little dehydrated. She is schedule for another ca-125 in a couple of weeks and will see her oncologist also. Has anyone had a similar situation and receive a ca-125 number on the next test. Thanks!

PS Mom I know you are reading this, I love you and you will get through this.
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I had something similar happen. Prior to my surgery to have cyst removed my CA 125 was at 23. After it's removal and the finding of tumor it was at 57...it's also common for it to go up after surgery. My oncol said I also had an abcess (abscess) and a UTI which he felt raised the number. After my first and all rounds of chemo it stayed at 10. I am sure the infection had something to do with it. It's hard not to worry I know!!
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Yes this is normal for the CA125 test to run higher with an infection, hopefully it will come back down when they get the yeast infection cleared up. With the scan clear that is a good sign also.  Good Luck and let us know how you come out.
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To be honest, much of the time the blood test will spike up before any cancer is actually seen on a CT scan. So, you can have an elevated CA125 with no visible cancer, but the test should be repeated monthly to keep an eye on things. I'm sure that the infection has much to do with the increase - when it's all cleared up, she should have the CA125 repeated. Is it a good marker for her?
Becky
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