Hi Dr.Goodman
I have started my second round of chemo with Taxol/carbo for a recurrence. I met with a new Dr at Princess Margaret Hospital in Toronto, who said it was more likely that I have a platinum resistant cancer. (I recurred at about 6.5 months) He told me he would not have started me on the same drugs as last time and gave me two options to try. One is the standard treatment for platinum resistant cancers (can't remember the name of the drugs, but I'm sure you know which ones they are) or he offered me a phase II clinical trial titled "A Phase II Study of PDX101 in Platinum Resistant Epithelial Ovarian Tumors and Micropapillary/Borderline(LMP) ovarian tumors". I have Micropapillary Serous Carcinoma, and he thought this would be good for me. Do you know much about phase II trials? It looks like I will be monitored very closely, but I can't help worrying about the side effects - they seem really similar to Taxol/carbo. How much do they know about a drug at this point? Is it safe to assume that they are obviously seeing good results from this? I would think that if they weren't, they would not be continuing on with it. He said he couldn't discuss any of the results from past expierences with this drug. What are your thoughts on trials? I can't help but think how amazing it would be to help find a treatment for MPSC, seeing as it is such an unpredictable, aggressive cancer.
Your thoughts would be greatly appreciated,
Sincerely,
Becky H