Recurrence after 4th line

[OVCIndia]

1st line 6 cycles iv taxol + carbo & 3 cycles IP cisplatin consolidation (1 Year Remission)

2d line 6 cycles iv carboplatin + Doxil ( No surgery) and PET/CT at end of treatment showed No Evidence of Disease ( 1 Year Remission)

3d line Gemzar + Avastin + Oxaliplatin (no surgery) and PET/CT at end of treatment showed No Evidence of Active Disease 7 month remission.

4th line 12 weekly taxol CA125 today which came in at 8.5 at end of treatment.  4 Months remission.

Her latest CA124 has gone up to 135.  Her performance status is very good and she has no symptoms currently.  What options do we have this time around?

[OVCIndia]

Thank you doctor goodman.  She has never had hormone therapy

[Annekathryn Goodman, M.D.]

Hi there

you should ask her doctor about trying carboplatin again
it looks like it has been over a year since she has seen platinum
other option include:
-doxil again
-topotecan
-avastin with cytoxan

has she ever been on hormone therapy such as tamoxifen?
please keep in touch
best wishes