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Which Chemo To Use
by AprLynn, Jan 24, 2008 12:23PM
In 2002 I had Stage 2A ovarian cancer and was treated with taxol & carboplatin for 6 cycles.. Also found out that I had the Brac 1 gene mutation. In 2005 I had bilateral breast cancer, had a double mastectomy, received TAC for 6 cycles. In Nov 2007 during a PET scan it was discovered that I had nodules on my lungs. CA 125 was 53. I had lung biopsy done and yes it was ovarian cancer metastasized to my lungs. The question was whether to use the original Taxol & carboplatin since the ovarion cancer stayed in remission for 5.5 yrs or to use Gemzar and Carboplatin because I have had both taxol and TAC. Could it be that these nodules are resistant to anything in the taxol family?
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In my case I was given Taxol and Carboplatin again when I recurred after 4 years but it wasn't effective. My oncologist reckoned at the time it had a 60% chance of working and the longer you go in remission the better your chances are that it is effective.
Though I would argue that I was so optimally debulked the first time that they have no idea if the chemo worked at all as there was nothing to measure.
Good luck with whatever you decide.