Which Chemo To Use

In 2002 I had Stage 2A ovarian cancer and was treated with taxol & carboplatin for 6 cycles..  Also found out that I had the Brac 1 gene mutation.  In 2005 I had bilateral breast cancer, had a double mastectomy, received TAC for 6 cycles.  In Nov 2007 during a PET scan it was discovered that I had nodules on my lungs.  CA 125 was 53.  I had lung biopsy done and yes it was ovarian cancer metastasized to my lungs.  The question was whether to use the original Taxol & carboplatin since the ovarion cancer stayed in remission for 5.5 yrs or to use Gemzar and Carboplatin because I have had both taxol and TAC.  Could it be that these nodules are resistant to anything in the taxol family?  

[hopeshell]

Just curious if anyone stage 1 ovca recur and if so how was it discovered and what were your symptoms.  Thanks.

[hopeshell]

oops..sorry about posting in the wrong place.  Hopefully, someone will be able to answer your post.  I am sorry to hear of your recurrence.  I'll be praying for you.

[kismetfarm]

I guess what your oncologist feels is the best way to go at this stage.  You went a long time without a recurrence so the Taxol and Carbo in theory worked.  

In my case I was given Taxol and Carboplatin again when I recurred after 4 years but it wasn't effective.  My oncologist reckoned at the time it had a 60% chance of working and the longer you go in remission the better your chances are that it is effective.  

Though I would argue that I was so optimally debulked the first time that they have no idea if the chemo worked at all as there was nothing to measure.

Good luck with whatever you decide.