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Ovarian Cancer  (Expert Forum)
 | 
chemo and heparin induced thrombocytopenia
Answered by
Annekathryn Goodman, M.D. - Gynecologic Cancers, Complex Gynecologic, Surgeries, Palliative Care, Acupuncture
Massachusetts General Hospital Cancer Center Boston - MA
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This forum is for questions and support regarding ovarian cancer issues, such as: Biopsy, Chemotherapy, Clinical Trials, Genetics, Hysterectomy,Immunotherapy, Ovarian Cancer Types, Radiation Therapy, Risk Factors, Screening, Staging, Surgery.

chemo and heparin induced thrombocytopenia

by Joyce2, Feb 12, 2007 12:00AM
Diagnosed with oc stage 3 12/05. Had taxol/carbo which stopped working in Aug. Next given cisplatin/Gemzar which was extremely hard on my platelets.  Now I'm being tested for HIT or heparin induced thrombocytopenia.  Platelets went down from 74,000 to 52,000 instead of going up.  Can't have chemo until I reach 100,000. Do you think the chemo is responsible for the continuing low platelets (haven't been able to have chemo for 4 weeks straight) or is this HIT responsible for the decrease.  How common is HIT when only heparin exposure is the heparin flush after blood draws and chemo. CA125 is currently over 4,000. Tumors were inoperatable.

by Annekathryn Goodman, M.D., Feb 14, 2007 12:00AM
Dear Joyce,

There is a test for HIT so it should be fairly easy to answer that question. Most likely your low platelets are from the chemotherapy. It must be very hard waiting for your counts to come up. You should ask your doctor about considering something like tamoxifen which has anticancer activity in some ovarian cancers and doe not affect blood counts

best wishes to you
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