single gene mutation breakthrough discovery

[sassysally]

The recent New England Journel of Medicine announcement of Canadian breakthrough for granulosa cell ovarian cancer single gene mutation discovery   -  how will that affect those of us with the disease [and our families?]
What does that all mean?      Fran

[sassysally]

I read article in the New England [anybody can] free -just go to thier site. I copied it for free as well.

Dr M. Birrer [Harvard director gyn/oncology  " the ovarian cancer research and care community now has new biologic insights into this poorly understood tumour  - study reveals the power of genomic approaches to cancer, particularly rare tumours."

"Found -one in three billion"  a spelling mistake in the genetic code that causes granulosa cell tumours - ,we can now easily identify them and develop new ways to treat them.  The characteristic single DNA "spelling" mistake can serve as an easy to read identity tag for this cancer type.
Lots in Canadian papers about it as discovered in Vancouver =  those having had this type of ovarian cancer  tell stories of the lengh of time for tumour identification  and lack of treatment available. And no useful bloodchecks for reoccurance identification.

[junamgen]

Do you have the link to the actual paper? My guess maybe just like the relation between BRCA1,BRAC2  and OVCA.

jun