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Drug reaction?

by orianna, Oct 24, 2008 10:17AM
Tags: reaction
I recently was changed from hydrocodone to methadone and by the second day i started to develop a body rash, a really fine very itchy rash,  starting on the trunk of my body and has now moved to include my hips and legs.  I had taken methadone before and never had any reactions.  I don't seem to find much on the net about meth and rashes, so I am wondering if the level of hydro is still up there enough to possibly be the mix causing this rash.  I finally took an antihistamine and half of one of my prednisone before bedtime, and it finally let me go to sleep with the severe itching subsiding somewhat.  

Anyone have an ideas or have had a rash reaction with methadone?  Thanks for any help!
Member Comments (6)

by jollyman069, Oct 24, 2008 10:25AM
sorry no but i think i would be calling either my pharmist or pain dr right away.. drug reactions are nothing to mess with.. i would think the pharmist would be the first call.. good luck and please let me know

by orianna, Oct 24, 2008 11:12AM
To: Thanks
Tried my doctor but neither his nurse or he are in today.  Will try the pharmacy.

by Mollyrae, Oct 24, 2008 11:27AM
Hello and welcome to MH.
Sorry to hear of the rash. It sounds medication related. There is a member here by the name of Tuckamore and she is very familiar with Methadone. She would be the one to help you with your concerns. She should be on sometime today to answer any questions you might have. I will also send her a PM.
Take care,
Mollyrae

by Tuckamore, Oct 25, 2008 10:17AM
Hi Orianna,

Welcome to the Pain Management Forum at MedHelp. I'm sorry you are having a reaction to your Methadone.  I apologize for not being here yesterday. I have been dealing with a nasty pain flare myself.

I certainly hope that by now you have stopped taking the Methadone. Sometimes we can take a medication such as penicillin (or in your case Methadone) for a number of years and all of a sudden our system develops an allergy to it. It is my understanding that this is a new prescription and you have not been on Meth for a long period of time. IF that is correct, you just began the Meth than until you have seen or discuss the rash with your prescribing physician STOP taking the Meth. The rash should not be from the two medications but anything is possible.

Additionally a medication reaction that produces a rash is usually NOT a fine pinpoint rash. Most med induced rashes look more like hives. They are a larger raised red blotchy looking rash. If you take your nail and run it firmly down your arm more hives will often appear beneath the nail path. I would look at other possibilities that could be causing the rash BUT until you are certain it is always safer to eliminate the "new" things in your environment and in your case that appears to be the Meth. Also you will usually notice a bit of an itchy or "sore" throat with a med reaction but not always. If you have any difficulty breathing you should call 911 immediately.

Again I am sorry I am late with my response. Please let us know how you are doing and be cautious.  Take care, Tuck


by Jaybay, Oct 25, 2008 10:26AM
Yikes!  In addition to Tuck's excellent advice, I'd get going on benadryl FAST.  I nearly stopped breathing with the antibiotic Biaxin a few years ago.  Thank God my husband had the presence of mind to stuff the benadryl down my throat or I would have been gasping out my last in an ER.  

Don't forget your insurance carrier as a resource.  Most companies have a nurse hotline available to clients 24/7.  If you can't reach your doctor, you might give that option a try.

by Tuckamore, Oct 25, 2008 11:24AM
To: Jaybay& Orianna
Jaybay, Thank goodness she did take an antihistamine (which is of course what benadryl is) along with prednisone. She did some quick, smart thinking. If she would have waiting on me...she may have been in ER.

Sorry I forgot to tell you Orianna, good thinking. Tuck
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