You CAN develop an allergy to a drug you've taken before or different drugs in the same class.
I had been itching miserably for days. I stopped taking all medications then added them back one by one. Oxycodone is the culprit. I was surprised because I took it off and on often before back surgey, then intensively after surgery. I haven't taken it for months, but the other med I was on caused stomach problems- so back to oxycodone I went. While looking for info about this strange new reaction to a drug I had taken before without problems, I found the following info on
"Allergic drug rash: Most allergic drug rashes start within two weeks of taking a new medication, especially if the person has taken the drug before. It is very unlikely for medicine that has been prescribed for months or years to cause an allergic reaction."
Thought I'd pass it along.
It's possible, although not too likely. You can develop an allergy to anything at all at any time, though. It can be something that you have taken or eaten for many years with no problem, but that one time can cause a problem.
Do you know if it's actually the oxycodone that you are having a problem with? Or could it be something that is in the tablet with it? The reason I ask is because before I started taking oxycodone, the drug that my doctor had me on for a while was Vicodin. I had absolutely no problem with it, and I took it for about 10 months before I started going to my current neurologist. He was the one who diagnosed me with adhesive arachnoiditis and, because this is an incurable condition and I will need pain meds for the rest of my life, he took me off the Vicodin and put me on Roxicodone because it comes in a pure form without any Tylenol in it, since long-term Tylenol is very dangerous for the liver. Well, one month he gave me my prescription, and off I went to the pharmacy. The pharmacist informed me that he was out of Roxicodone, and that it would be three days until it came in. He called my neurologist for a prescription for something so that I wouldn't go through withdrawal while I was waiting for the Roxicodone to be delivered. My doctor had to give me something that could be called in over the phone, so that let out any Sched. II drugs, so he called in sixty 10mg Vicodin (Norco) tablets for me. Now, Norco only has 325mg of Tylenol in it, and I had taken it for 10 months before I started going to this guy. I was sick beyond belief from the Tylenol in the Norcos! I couldn't hold down any food at all, and I ended up having to force myself to take even one tablet every six hours instead of two every four hours. By doing it that way, I was pukey for about two hours after I took the tablet, but at least I was able to stave off withdrawal symptoms. But three years before, the Norco was the drug that I took to help my pain, and I took it with absolutely no problems. At first I thought it was the hydrocodone that was making me sick, but not too long ago I had a headache (the narcotics don't help headaches, at least they don't help mine) and I usually take Advil to get rid of a headache. I was out of Advil, but I had one of those purse-sized thingies of Tylenol, so I took two of those. Within an hour I was all pukey again, and then it hit me, it wasn't the hydrocodone that I had been sick from, it was the Tylenol (APAP) in them! I had never had a problem with Tylenol before, but now I can't take them at ALL. Maybe try asking your doctor for Roxicodone instead of Percocets?
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