I was diagnosed with mild PD 6 years ago, I have been using the requip XL for quite a while without any problems. I do take some other medications too, but found the long acting eliminated the on and off fluctuations, and happily with my current combination of medications I have no visible symptoms. For me it made a big difference when I switched from the ropinerole that needs to be taken 3 times a day .Hope this helps you
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