Down's syndrome

5 year old granddaughter  who initially was found to be slightly hypothyroid  at age 4.  Started on rx to treat then became slightly hyperthyroid.  Rx was stopped over 3 months ago but child has continued to become even more hyperthyroid  lab wise as well as clinical signs.  Your opinion please

[Deanna L Aftab Guy, MD]

Well hard to tell without the labs and seeing the patient, be sure that she is with a pediatric endocrinologist and have her parents sit down and obtain a clear idea of what is going on. I have a few patients with Down Syndrome who are hyperthyroid, ,and a bunch more hypothyroid. It is possible, both in the same child. They are prone to autoimmune diseases and thyroid disease is very common.