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Pediatric Endocrinology (Expert Forum)
PLEASE HELP WITH RESULTS !!
Answered by
Deanna L Aftab Guy, MD - Short Stature, thyroid, Pituitary abnormalit, Puberty concerns, Rapid Growth, Adrenal problems, Parathyroid abnormal, Rickets and bone dis
Vanderbilt Children’s Hospital
Nashville - TN
Questions in the Pediatric Endocrinology forum are answered by Dr. Deanna L Aftab Guy, affiliated with Vanderbilt Children's Hospital. Topics covered include adrenal problems, diabetes insipidus, menstrual irregularities, obesity, parathyroid abnormalities, pituitary abnormalities, puberty concerns, rapid growth, rickets and bone disease, short stature, and thyroid.
PLEASE HELP WITH RESULTS !!
by bobo27, Sep 08, 2008 05:08AM
Hi Please if anyone could help tell me what my 10 year old daughters lab test mean that would be great. She has been unwell for ten months and not getting any better!
TSH 11.49
T4 13.9
ESR 45
positive ANA titre 1:80
thyroid peroxidase 1066.0
thyroid microsomal Ab titre of 1 in 6400 Thanks to anyone who can help Sue xxx
TSH 11.49
T4 13.9
ESR 45
positive ANA titre 1:80
thyroid peroxidase 1066.0
thyroid microsomal Ab titre of 1 in 6400 Thanks to anyone who can help Sue xxx
Doctor's Answer
by Deanna L Aftab Guy, MD, Sep 13, 2008 09:24PM
, Sep 13, 2008 09:24PMTo: bobo27
I would work very closely with your pediatrician and ask for referral, with positive antibodies, elevated tsh this is hypothyroidism, they need to get a free T4, to decide if this is subclinical hypothyroidism, If the free T4 is low then she would benefit from treatment.
Hashimoto's thyroiditis is the most common form of hypothyroidism other than iodine deficiency in certain areas of the World. It is caused by autoimmune destruction of the thyroid gland. Mostly all patients have positive antibodies to one or both of the thyroid antigens like you have above thyroglobulin and thyroid peroxidase. It can be precipitated by infection, stress, steroids, radiation exposure and iodine.
Treatment is with thyroid hormone in the face of hypothyroidism.Thyroid hormone is critical for neurological, cardiovascular, gastrointestinal and overall metabolic and reproductive needs. monitoring of dosing and labs to assess response to treatment is key to adequate replacement.
Hashimoto's thyroiditis is the most common form of hypothyroidism other than iodine deficiency in certain areas of the World. It is caused by autoimmune destruction of the thyroid gland. Mostly all patients have positive antibodies to one or both of the thyroid antigens like you have above thyroglobulin and thyroid peroxidase. It can be precipitated by infection, stress, steroids, radiation exposure and iodine.
Treatment is with thyroid hormone in the face of hypothyroidism.Thyroid hormone is critical for neurological, cardiovascular, gastrointestinal and overall metabolic and reproductive needs. monitoring of dosing and labs to assess response to treatment is key to adequate replacement.
