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Pediatric Endocrinology   (Expert Forum)
 | 
mildly elevated cortisol
Answered by
Deanna L Aftab Guy, MD - Short Stature, thyroid, Pituitary abnormalit, Puberty concerns, Rapid Growth, Adrenal problems, Parathyroid abnormal, Rickets and bone dis
Vanderbilt Children’s Hospital Nashville - TN
Questions in the Pediatric Endocrinology forum are answered by Dr. Deanna L Aftab Guy, affiliated with Vanderbilt Children's Hospital. Topics covered include adrenal problems, diabetes insipidus, menstrual irregularities, obesity, parathyroid abnormalities, pituitary abnormalities, puberty concerns, rapid growth, rickets and bone disease, short stature, and thyroid.

mildly elevated cortisol

by sue3708, Apr 11, 2008 05:53AM
What is the effect of mildly elevated cortisol over time if cushings is ruled out with an overnight dex. test. and remains slightly elevated in 24 hour urine?

by Deanna L Aftab Guy, MD, Apr 11, 2008 08:19AM
To: sue3708
Cortisol can be mildly elevated in cases of depression or other stressors to the adrenal gland, cortisol itself is a hormone that raises blood sugar, can raise blood pressure, increase storage of energy such as fat and mobilize bone causing problems with osteoporosis, create some insulin resistance leading to risks of diabetes.
I would clearly work with your endocrinologist to discuss what exactly is your level and if it is normal and now that the tests have been done what is next. Sometimes 2-3 collections of urine are needed or it may be early, the overnight dex test rules out that there is a source that is acting on its own and shows that the thermostat is able to be shut off properly. Keep working with your doctor
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