Pediatric Heart Expert Forum
2mm mid muscular VSD
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2mm mid muscular VSD

My wife is positive SSB, positive ANA.  Mother-in-law is diagnosed with Sjogrens(2009) with ITP(idiopathic
thrombocytopenic purpura)

Unborn Baby diagnosed with tiny mid-muscular VSD. Size not recorded during fetal echocardiogram
done at 28 weeks by paediatric cardiologist. The cardiologist mentioned  "at most 2mm" later on.
ECG will be done on birth.

Since the size is likely small, it may close on it's own. We will be observing baby's growth,
feeding, and signs of sweating.

1) Should we preserve cord blood with a private blood bank?  Since heart valves have been grown from
cord blood stem cells, can these cells have a future application for curing VSD?

2) If the child is male, then his children may have 5-8% chance of congenital heart defect.
This has been mentioned somewhere. What if the child is female?

3) Is Eisenmenger's syndrome(right-to-left shunt) ruled out for a small VSD?

4) Do children have any restrictions on physically intensive sports or other quality of life issues?

Very concerned...
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Small ventricular septal defects are common and usually do not cause any cardiac symptoms or growth retardation.  If the remainder of the child's heart is normal, and the child has no other medical issues, there would be no activity or lifestyle restrictions.  Small VSDs generally do not require surgical intervention.  So saving cord blood for this purpose is not necessary, But if you desire it for other reasons, then that is a personal decision. If a female has congenital heart disease, then her offspring will have a 5-10% chance of having a congenital heart issue.  The risk for the offspring is 3-5% if the father has congenital heart disease.
Eisenmenger syndrome is a late complication of years of high blood flow to the lungs under high pressure, such as in an unrepaired large VSD.  That should not occur with a small VSD.
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Jeffrey R Boris, M.D.Blank
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