Pediatric Heart Expert Forum
Did the medication cause the problem?
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Questions in this forum are answered by pediatric cardiologists, cardiothoracic surgeons and anesthesiologists from The Children's Hospital of Philadelphia. This forum is for questions and support about pediatric heart problems, symptoms and topics such as heart murmurs, palpitations, fainting, chest pain, congenital heart defects (including management and intervention), fetal cardiology, adult congenital cardiology, arrhythmias and pre-participation athletic screening.

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Did the medication cause the problem?

I had my daughter about a month ago and she was born with d-transposition along with ASD, VSD, and pulmonary stenosis. I have a seizure disorder and started taking Trileptal later on in my pregnancy. Could it have still caused the problem?
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Dear ttransue: The heart is completely formed by 8 to 13 weeks gestation, sometimes even before women know that they are pregnant.  Therefore, the first trimester is the most critical when talking about the impact of medications taken by the mother upon the developing fetus.  During the second and third trimesters, the fetal heart grows more in size, but the anatomy and function is much less likely to be impacted by medication.  Trileptal is considered a pregnancy category C medication, meaning that in animals there have been issues when administered to animals in the first trimester.  However, if you started taking the anti-convulsant medication later in pregnancy, after the first trimester, it likely has nothing to do with the congenital heart disease in your child.
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