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Does anyone has done blood test that shows: high Eosinophils and high B12?
High eosinophils= high histamine ( histamine is involved with allergic reaction. people may be reacting to this high histamine maybe from our breath), most likely low DOA ( enzymes that break histamine).
B12 involves with blood.
B12 involves with blood.
A high eosinophil count may be due to:
•Allergic disease.
•Parasite infection, such as worms.
•Certain fungus infections.
•Asthma.
•Autoimmune diseases.
•Eczema.
•Hay fever.
•Leukemia and other blood disorders
•Allergic disease.
•Parasite infection, such as worms.
•Certain fungus infections.
•Asthma.
•Autoimmune diseases.
•Eczema.
•Hay fever.
•Leukemia and other blood disorders
1 Comments
Yes and my doc is not bothered about this but i am. i treated my h pylori and retest negative.
I am just waiting to see the GI consult to get endoscopy and see what comes out of it. if my patm and GI symptoms still continues and eosinophils still high, i will definitely ask for further tests and other specialists. I also saw an ENT, going back on Monday. maybe i will ask for lungs endoscopy, i don't know.
For sure, i do not have Asthma, pulmonary function test and x-ray negative.
So how is life after patm ray? still no reactions from people?
I am just waiting to see the GI consult to get endoscopy and see what comes out of it. if my patm and GI symptoms still continues and eosinophils still high, i will definitely ask for further tests and other specialists. I also saw an ENT, going back on Monday. maybe i will ask for lungs endoscopy, i don't know.
For sure, i do not have Asthma, pulmonary function test and x-ray negative.
So how is life after patm ray? still no reactions from people?
My Eosinophils are low. The value I got for EOS is 1.1%, and the normal range is 0.5-5.5%. For EOSA, my value is 0.07 (0.02-0.50 is normal).
I haven't had my B12 levels checked, but my thrombozytes are low: 139 (150-370 is normal). My hematocrit value is also slightly low: 38.0% (39.5%-50.5%).
I also have a weird finding where my total serum protein count is low: 6.1 (6.6-8.7). But the particular protein albumin is somewhat high: 66.6% (55.8%-66.1%). So my total protein count is low, but one particular protein of that total is high. I've been looking around to see if that means anything, but haven't found anything yet.
Over the last two years, my liver enzymes (AST, ALT, and AP) were slightly high, but I've recently gotten those numbers well within the normal range (by giving up alcohol and trying all sorts of supplements: protein powder, SAMe, N-acetylcysteine, and B vitamins).
I think there might be something to the histamine hypothesis. Even though my blood tests have come back (mostly) normal, I've noticed that my veins are much more dilated than they've ever been before, and I've read that histamine can do this. I've also wondered if we might be releasing bradykinin on our breath (i.e., maybe we have tissue inflammation somewhere in our bodies, e.g., intestines, and this inflammation triggers the release of bradykinin). Bradykinin can cause uncontrollable urges to cough as well.
A weird thing, though, is why this histamine, bradykinin, or whatever it is, doesn't reliably cause us to cough as well? Maybe our immune systems are built-up against our own self-produced histamine or bradykinin?
I haven't had my B12 levels checked, but my thrombozytes are low: 139 (150-370 is normal). My hematocrit value is also slightly low: 38.0% (39.5%-50.5%).
I also have a weird finding where my total serum protein count is low: 6.1 (6.6-8.7). But the particular protein albumin is somewhat high: 66.6% (55.8%-66.1%). So my total protein count is low, but one particular protein of that total is high. I've been looking around to see if that means anything, but haven't found anything yet.
Over the last two years, my liver enzymes (AST, ALT, and AP) were slightly high, but I've recently gotten those numbers well within the normal range (by giving up alcohol and trying all sorts of supplements: protein powder, SAMe, N-acetylcysteine, and B vitamins).
I think there might be something to the histamine hypothesis. Even though my blood tests have come back (mostly) normal, I've noticed that my veins are much more dilated than they've ever been before, and I've read that histamine can do this. I've also wondered if we might be releasing bradykinin on our breath (i.e., maybe we have tissue inflammation somewhere in our bodies, e.g., intestines, and this inflammation triggers the release of bradykinin). Bradykinin can cause uncontrollable urges to cough as well.
A weird thing, though, is why this histamine, bradykinin, or whatever it is, doesn't reliably cause us to cough as well? Maybe our immune systems are built-up against our own self-produced histamine or bradykinin?
5 Comments
since i started noticing this patm, my eosinophils has been very high >1000 ( 15-500) and my doc said there is nothing wrong. I tested negative for more than 60 allergens, but I sneeze here and there. And yes, per ray2502, high eosinophils can be due to lots of things but allergic reaction is what most pple think of when they see high eosinophil. I used claratin, benedryl, per doc but eosinophils still high.
I tested positive for hyplori, treated with antibiotic ( i took lots of probiotics as well). I had to treat it twice,retest shows negative. But eosinophils still high. what i don't know is if this is my normal. but patm got me worrying and wondering. Aside from patm and occasional gastrointestinal disturbances, i am a very health person.
For my B12, this is also my first time checking it and it was high. Although i used B12 supplements not long ago but i am worried because b12 is a water soluble vitamin so it shud not linger in my blood but, again, doc said it is ok ( i don't believe that one bit. i will stop my supplement and retest in a month or two). The reason i asked my doc for this test is because i was have occasional twitch, and i thot i was likely deficient, but ii was wrong but i am glad i checked it.
For your high albumin, it might be due high protein diet or the protein powder you took, usually, this protein pulls water into your blood vessel and that cause more fluid and thus dilated vessel. For me, all my protein are normal.
my liver enzymes test is normal now, AST was high right after my hyplori treatment, but it normal range now.
All my labs are normal except for the eosinophil and b12 ( high), i am healthy and feel great except for occasional GI issue, so i really don't know what this patm could be. The only thing i got to work with now is the histamine. I will be seeing a GI consult in 1 1/2 month. i will be asking for endoscopy.
For people thinking this is a mental illness, this is absolutely not. how can someone make up all the obvious reactions from people, this is not a coincidence. I am a very happy person, not depressed but patm is making me for sure.
For bradykinin, this can build up due to a blood pressure medication and it can cause cough. I am thinking that even if we have high histamine, bradykinin, shouldn't we be that only one reacting? why are other people reacting?. like you said, this has to be something from the breath.
I also notice that when i just finish eating, people react more. in fact, my patm reduced a little bit when i did not eat ( i did not eat to class for about three weeks, and few people reacted. i usually eat when i get home).
I tested positive for hyplori, treated with antibiotic ( i took lots of probiotics as well). I had to treat it twice,retest shows negative. But eosinophils still high. what i don't know is if this is my normal. but patm got me worrying and wondering. Aside from patm and occasional gastrointestinal disturbances, i am a very health person.
For my B12, this is also my first time checking it and it was high. Although i used B12 supplements not long ago but i am worried because b12 is a water soluble vitamin so it shud not linger in my blood but, again, doc said it is ok ( i don't believe that one bit. i will stop my supplement and retest in a month or two). The reason i asked my doc for this test is because i was have occasional twitch, and i thot i was likely deficient, but ii was wrong but i am glad i checked it.
For your high albumin, it might be due high protein diet or the protein powder you took, usually, this protein pulls water into your blood vessel and that cause more fluid and thus dilated vessel. For me, all my protein are normal.
my liver enzymes test is normal now, AST was high right after my hyplori treatment, but it normal range now.
All my labs are normal except for the eosinophil and b12 ( high), i am healthy and feel great except for occasional GI issue, so i really don't know what this patm could be. The only thing i got to work with now is the histamine. I will be seeing a GI consult in 1 1/2 month. i will be asking for endoscopy.
For people thinking this is a mental illness, this is absolutely not. how can someone make up all the obvious reactions from people, this is not a coincidence. I am a very happy person, not depressed but patm is making me for sure.
For bradykinin, this can build up due to a blood pressure medication and it can cause cough. I am thinking that even if we have high histamine, bradykinin, shouldn't we be that only one reacting? why are other people reacting?. like you said, this has to be something from the breath.
I also notice that when i just finish eating, people react more. in fact, my patm reduced a little bit when i did not eat ( i did not eat to class for about three weeks, and few people reacted. i usually eat when i get home).
I also notice increased reactions after eating, especially anything pungent like herbs or steamed vegetables. The two hypotheses about PATM I've been entertaining are that: 1) it's similar to secondary TMAU, in which our gut is creating (or failing to neutralize) some noxious chemical (e.g., trimethylamine, histamine, or maybe even ozone - Google: "Antibodies produce ozone during bacterial killing and inflammation"), and these noxious chemicals escape on our breath and in our sweat. The other hypothesis is that: 2) PATM has something to do with odors or chemicals escaping from the stomach. I base the second hypothesis on my increased odors after eating and on the fact that my endoscopy revealed gastritis. My PATM reactions also significantly increased when I tried a proton pump inhibitor, so any kind of perturbation to my stomach functioning seems to be associated with increased PATM.
My gastroenterologist didn't find h. pylori, so I think my gastritis was caused by drinking too much alcohol and foolishly trying to use spices like cinnamon as homeopathic remedies. I think I'll also try to get my B12 levels assessed at my next doctor's appointment, just to see if mild anemia might be an issue.
Your increased B12 levels are interesting because I thought stomach problems usually resulted in decreased B12 levels, since B12 requires intrinsic factor from the stomach lining. Previous posters (observer_PATM) had anemia and actually recommended B12 supplementation to help alleviate PATM (although I suspect the blood transfusion she got probably had the greater effect on her PATM). I suppose increased B12 might indicate an issue with the kidneys, and kidney problems can sometimes cause secondary TMAU - Google: "Trimethylaminuria (fish malodour syndrome) in chronic renal failure".
My increased vein dilation did start when I began taking protein powder, so it's good to know that that might be the cause (although I gave up protein powder 6 months ago and my veins are still noticeably large).
It would be so helpful if we could just figure out what substance our bodies are producing to make people cough. Right now, it's all just guesswork. It does seem like it should be something like histamine, because people react so severely to it (at least in my case), and I'm not sure even the foulest odor would cause such severe coughing (i.e., it's got to be something really irritating to people's airways). It also doesn't have to build in concentration to have its effect (which would argue against it being something like ozone) - I cause people to cough even out in fresh air. So the bottomline is that the substance has to be volatile and severely irritating, but other than that, everything is just a hunch.
My gastroenterologist didn't find h. pylori, so I think my gastritis was caused by drinking too much alcohol and foolishly trying to use spices like cinnamon as homeopathic remedies. I think I'll also try to get my B12 levels assessed at my next doctor's appointment, just to see if mild anemia might be an issue.
Your increased B12 levels are interesting because I thought stomach problems usually resulted in decreased B12 levels, since B12 requires intrinsic factor from the stomach lining. Previous posters (observer_PATM) had anemia and actually recommended B12 supplementation to help alleviate PATM (although I suspect the blood transfusion she got probably had the greater effect on her PATM). I suppose increased B12 might indicate an issue with the kidneys, and kidney problems can sometimes cause secondary TMAU - Google: "Trimethylaminuria (fish malodour syndrome) in chronic renal failure".
My increased vein dilation did start when I began taking protein powder, so it's good to know that that might be the cause (although I gave up protein powder 6 months ago and my veins are still noticeably large).
It would be so helpful if we could just figure out what substance our bodies are producing to make people cough. Right now, it's all just guesswork. It does seem like it should be something like histamine, because people react so severely to it (at least in my case), and I'm not sure even the foulest odor would cause such severe coughing (i.e., it's got to be something really irritating to people's airways). It also doesn't have to build in concentration to have its effect (which would argue against it being something like ozone) - I cause people to cough even out in fresh air. So the bottomline is that the substance has to be volatile and severely irritating, but other than that, everything is just a hunch.
Yeah, this patm reactions from people are from our breath, however, we don't know the problem is in the body. But gastrointestinal is a very good hypothesis as well as the blood. I have actually hold my breath /cover my nose and mouth with my jacket and no reactions from people around me in class.
so what did you do for your gastritis?
I actually checked my B12 because i thot maybe i was deficient because of occasional twitch i have but it turns i have high level. yeah high b12 ca be liver or kidneys but these two organs are normal for me. or it can also be blood disorder problem. After my GI, i will ask my doc for hematologist referrals.
For your dilated veins, make sure you exercise to help move blood.
so what did you do for your gastritis?
I actually checked my B12 because i thot maybe i was deficient because of occasional twitch i have but it turns i have high level. yeah high b12 ca be liver or kidneys but these two organs are normal for me. or it can also be blood disorder problem. After my GI, i will ask my doc for hematologist referrals.
For your dilated veins, make sure you exercise to help move blood.
For gastritis, I adopted a very bland diet, eliminating all spices, seasonings, and alcohol. For a couple of months, I also gave up coffee, but I've gone back to it - life needs to be enjoyed too, and coffee doesn't cause me any heartburn anymore, so I think I can tolerate it (although coffee is a big thing to avoid if you have severe gastritis).
I've also tried to consume soups instead of solid foods as much as possible, and I chew my food a lot more as well. I haven't had noticeable heartburn for a year or so, so I think my gastritis is under control, but I still wonder if there might have been some long-term damage to my stomach lining from it. I also tried zinc-carnosine (PepZin GI), but that didn't seem to have any noticeable effect for me.
I've noticed that I sometimes cause PATM reactions when I cross/uncross my legs or move my body a lot (e.g., if I'm jolted around on the metro), so I think, in my case, the PATM irritant also comes out of my sweat glands, dead skin cells, etc. But I think it definitely also comes out on my breath as well. When I first wake up each morning, I can smell a slight fecal odor on my breath, but it goes away (or I stop noticing it anyway) after a few minutes (i.e., when my mouth starts producing more saliva again). So I sometimes wonder if I'm giving off a fecal odor on my breath, but I still don't understand why that should make people cough so uncontrollably (sure, nobody likes inhaling fecal-smelling material, but I think one would have to be an exceptional jerk to make such a big deal of it by coughing so loudly for everybody to hear it).
I've also tried to consume soups instead of solid foods as much as possible, and I chew my food a lot more as well. I haven't had noticeable heartburn for a year or so, so I think my gastritis is under control, but I still wonder if there might have been some long-term damage to my stomach lining from it. I also tried zinc-carnosine (PepZin GI), but that didn't seem to have any noticeable effect for me.
I've noticed that I sometimes cause PATM reactions when I cross/uncross my legs or move my body a lot (e.g., if I'm jolted around on the metro), so I think, in my case, the PATM irritant also comes out of my sweat glands, dead skin cells, etc. But I think it definitely also comes out on my breath as well. When I first wake up each morning, I can smell a slight fecal odor on my breath, but it goes away (or I stop noticing it anyway) after a few minutes (i.e., when my mouth starts producing more saliva again). So I sometimes wonder if I'm giving off a fecal odor on my breath, but I still don't understand why that should make people cough so uncontrollably (sure, nobody likes inhaling fecal-smelling material, but I think one would have to be an exceptional jerk to make such a big deal of it by coughing so loudly for everybody to hear it).
God Bless you PATMsufferer !
Have you researched and checked out Diatomaceous Earth food grade ?
I have great patm free results with it and my plant based food choices and other supplements etc.
Have you researched and checked out Diatomaceous Earth food grade ?
I have great patm free results with it and my plant based food choices and other supplements etc.
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