I have a book called "Stop Prediabetes Now" written by Jack Challem. He has a section on PCOS and says to take N-acetylcysteine 600 mg three times daily. He says in a study, this led to significant decreases in testosterone and insulin in women with PCOS. IT said that testorone levels dropped by more than half and insulin levels declined by about one-third in four weeks.
I then googled it, and found many websites stating the same thing. Here is one site for example:
Has anyone tried this and if so, did you have any results?
I didn't see any side effects listed. It's just a suppliment, so hopefully nothing harsh. I'm on Metformin for PCOS so I emailed Life Extension, the company where I buy my vitamins and asked them if it was okay to take both. I haven't heard back yet though.
This was my response to my question about taking this with Metformin:
Thank you for your recent correspondence.
We are sorry to hear about your health condition.
Life Extension has not seen any evidence suggesting that n-acetylcysteine would be contraindicated with metformin.
On a side note, because metformin may cause malabsorption of vitamin B12, we would suggest taking methylcobalamin to maintain optimal B12 status. Life Extension offers this product in 1mg or 5mg dose; here are links to the description of this product:
There is some evidence that suggests that NAC can help with PCOS.
NAC is an incredibly versatile antioxidant that is used for all sorts of conditions including obsessive compulsive disorder, hair pulling, bipolar depression, schitzophrenia, cocaine addiction, alcoholism and unipolar depresssion. It is used to treat people who have overdosed on paracetamol and can help with excess mucous!
If you type in n-acetylcysteine in a seacrh engine you will get heaps of results (including lots of research papers).
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