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Metformin and Provera, trying to get pregnant

Hello,

My husband and I are trying to get pregnant with our first baby. I was diagnosed with PCOS a couple of weeks ago.
My OBGYN put me on Metformin and 10 days of Provera. I started taking both together - I am on my last pill of Provera, and now taking 1000 mg of Metformin (increased from 500 mg the first week).

I know Provera should induce my period, but does this mean that I am ovulating as I'm taking metformin? Or does my next "natural" period while I am on Metformin mean that I am ovulating.

My husband and I are TTC and I don't know when the best time is to "try".

Thanks! .
24 Responses
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Avatar universal
I have PCOS and I was given Provera and Metformin however, this month is my first month taking Metformin. I have been taking Provera and Metformin for 16 days and yet I have not started my period. Last month when I took Provera by itself it only took 7 days to start my period. Is Metformin stopping Provera from working?
Helpful - 1
Avatar universal
10 days
Helpful - 0
Avatar universal
i got pco and i was given  metformin and i caught pregant with my son  its the best thing thats ever happened to me i didnt take anything elso tho i also got the really bad hair growth and weight gain my son is now 5 months old and im trying to lose weight now but its very hard with pco as im about 17 stone :( and its getting me down....
Helpful - 0
Avatar universal
I have PCOS and have very irregular periods. What's the best time to take provera 5 days or 10? My doctor told me 5 days.
Helpful - 0
Avatar universal
I was on metformin for over a year and it did nothing. Immediately after taking clomid for the first time we got pregnant! I am happy to say that I am almost 31 weeks with our first. I highly suggest taking progesterone to have a period and then clomid to ovulate. It works miracles!
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Avatar universal
trying to conceive
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Avatar universal
what does TTC MEAN.
Helpful - 0
Avatar universal
I have PCOS, and have been TTC for 2 years. I have been through an assessment cycle with a fertility doctor and found I wasnt ovulating. I have started Metformin and my dr has told me to come back in two weeks to be started on Clomid. I have read so many of everyone's stories, and to be honest the whole thing confuses me. So I start Metformin, then need to go onto Clomid, and then Provera if my period doesn't start? Does this sound right? I have never been pregnant, and I haven't had a period for months (approx 4 months) and the last one i hate lasted for 2 months until Primulet stopped it. (I was losing too much blood) I just want someone to explain things to me in the most basic way. I get so upset with myself, I just need some guidelines.
Thanks
Helpful - 0
4966846 tn?1361715467
I feel cheated less then a woman 3 miscarriages 1 c section live birth. A Bad relationship of 15 years ended but I wanted another child so my daughter wouldn't be alone in this world had fibroids got them removed got all my female parts. In new relationship got my married this time around for a year tried to conceive nothing went to obgyn took sonogram said everything looked fine had blood work said starting the change but I hear those test can be wrong irregular period is my first reason I went to ob started me on Provera  I wonder if my periods get regular will I be able to ovulate I feel cheated that God has done this to to me and no child be the only one they should have a sibling/s thank you
Helpful - 0
4966846 tn?1361715467
Can the testing for menopause be wrong ? And can it be stopped if you are just beginning ? Can you get pregnant before it is to late ? provera assist in regulating your periods but do u ova late or not ?
Helpful - 0
Avatar universal
i am worried i was diagnosed with pcos after irregular period my gyno at the time had put me on a cycle of clomid only but it didn't work so i changed my gyno this new one put me on metformin last month still didn't ovulate and my period has n0t returned so he has prescribed provera clomid and metformin has anyone tried the combination and has it worked been TTC for over six months i'm not over weight.
Helpful - 0
Avatar universal
Hi again,
I'm so anxious which is probably not the greatest thing to feel since I feel like I'm putting more pressure on myself and my body to get pregnant!
I keep looking for signs that I'm pregnant...so disheartening.

I'm going to pick up an ovulation kit this week - I tried doing the "look out for egg-white-like-discharge" method, so we'll see what works for me!
Helpful - 0
1434731 tn?1382722384
Just having PCOS your chances of having a MC goes up!  

The Ovulation kits don't work for everyone!  Its all so confusing until you have been doing it for a while and get the hang of things!  Just ask lots of questions!

there are plenty of ppl in here that love to help other with advise!  ( i try)
Helpful - 0
Avatar universal
As my friend lynnie pooh said it's kind of true that in PCOS sometimes clomid does not work unless if you are overweight and loosing weight will really help. i myself was shocked that i got pregnant in my 6th round of clomid and with metformin. but it ended up in MC.
my doctor was shocked herself because she said she had never gotten any women in PCOS getting pregnant with clomid. i was actually ovulating every month. i use to use kit and it use to give me light positive line. but never had any success.
when they give you  clomid doctors don't tell you one thing that there are only about 20-25% chance that you will get pregnant. clomid is very good with returning you cycle back to normal :). according to my research about 30-40% of people who get pregnant with clomid end up with MC in there first round. i am not trying to scare but share my experience. if any of you women are underweight or over weight maintaining your weight will help alot. i hope it helps :)
Helpful - 0
1434731 tn?1382722384
Hi,

I also have PCOS and was ttc... I spoke with my doc and he started me on metformin and povera.  I stopped taking metformin after about a month because the tummy problems never went away! (sorry TMI )  Well I used provera from sept 2010 - May 2011 and did not ovulate once even with 3 of those months including Clomid.  Provera does not make you ovulate it just induces a period, metformin lowers your insulin and clomid is for ovulation.  Clomid doesn't work for everyone.

SO I found a local doctor doing a clinical trial for women ttc with pcos.  started **** testing and it was found (may 2011) that I have endometrial hyperplasia (thickened uterine lining) and i will be seeing my regular gyno to have a d&c and have that linning byopsied to be sure its not cancer! I have to wait till Jan do to my insurance!  stupid 6 months waiting period!

I suggest in a couple months if you have not ovulated with the help of meds, start having some testing done.  Have a transvaginal ultrasound. Hysteroscopy (to check your tubes)!  

You can try ovulation kits... I always got the brand ANSWER and it comes with 20 sticks.....you pee in a cup, dip the stick and wait!  if the test line is as dark as the control line, you are ovulating and need to have sex right away.  if not then you aren't   ( i never got a positive)  you might also want to learn about taking your temp every morning...it is very helpful!  
Helpful - 0
Avatar universal
It's frustrating to get a period after a few months (thanks to Provera)...and then not know if I'm ovulating...sigh.
Anyone have any luck with ovulation kits? How do they work?
Helpful - 0
Avatar universal
So I don't know but I was diagnosed w/ PCOS and my doctor had to induce me in 7.2011 and since then my period was on time. My boyfriend and I have been TTC and I am 4 days late what could this be?
Helpful - 0
Avatar universal
There's are some concerns that sometimes women do ovulate during spotting time etc. however i would recommend you see your doctor as soon as possible for this spotting matter. it could be an infection or you might need a scan to see whether linning of uterus is not thickened too much... i would say see your GP
Helpful - 0
Avatar universal
Hi there can anyone help me with my concern.!Im on my second cycle of clomid and today is my 18th day of period.Still spotting persists.Its very frustrating to do intercourse when spotting is there.But is there a chance to get pregnant if you are having spotting........???
Helpful - 0
Avatar universal
Even though you may bleed doesn't mean you're ovulating. It could be just the uterine lining breaking down. Best way of telling for sure is thru lab work. But, DIY by charting(temping, CF(m), and what you feel that's going on 14-16 days before you period.
Helpful - 0
1564074 tn?1334490908
I was diagnosed with PCOS in August and given metformin to try to regulate my periods so we could TTC without the help of anything else. After only taking it for 2 1/2 weeks I was about to take progesterone to make me start my period. I did a HPT to be sure I was not PG. To my complete surprise I was! After a few test, the doctor realized that it was a tubal pregnancy and I had to receive a shot to have it removed before it hurt me. We are just now able to TTC because of the birth defects that the shot could cause if we tried before.

Before metformin I had my periods once every three to four months now I have it about every 30 days. I can now chart my ovulation which is nice! Metformin worked for me but it can also be paired with Clomid if you want to increase your chances!

The best time to try depends on how long your cycle is. SO until you determine that just have a lot of fun!!  
Helpful - 0
Avatar universal
Metformin may help you ovulate of you may need clomid.
Helpful - 0
Avatar universal
Provera is derived from the female hormone progesterone. You may be given Provera if your menstrual periods have stopped or a female hormone imbalance is causing your uterus to bleed abnormally. Provera is also prescribed to prevent abnormal growth of the uterine lining in women taking estrogen replacement therapy. Some doctors prescribe Provera to treat endometriosis.

Because provera is derived from progesterone, it is used to regulate the uterine lining. For women who bleed too often or not at all, Provera will regulate the problem so that they can have a normal period. It doesn't block a gateway or open a gateway, what it's doing is causing the endometrial lining to thicken and then shed, as progesterone would do naturally, if your hormones were in balance.

If you have no other problems such as PCOS, HSG etc i think you are good to go because you will be ovulating. now all you have to do this count the days of your cycle. i was told by my gynae that having sex every 2nd day after your cycle you don't miss any day. and you have high chance of getting pregnant. so get busy and have sex every second day. :)
Helpful - 0
Avatar universal
Im pretty sure anytime you have a period, you are supposed to ovulated. The metformin helps regulate ur periods by lowering your insulin levels. Try bbt charting, its helped me figuring out how my cycle is and when im ovulating.
Helpful - 0
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