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If she has a sinus infection, she should probably take an antibiotic. She can take certain antibiotics even though she is pregnant. If she is this sick and it's not going away on its own, this is probably what she needs. I have 5 kids and have taken antibiotics at one time or another with all of them. They are all fine; no problems whatsoever. WomenWomen's way who are pregnant are more likely already to get yeast infections though. Antibiotics will increase the risk of that even more unfortunately.