Aa
Aa
A
A
A
Close
1660049 tn?1326089018

PCOS and Metformin

Hi all I am 37, 1 mc and doc says I have PCOS. My husband and I are ttc. I was put on metformin 1000mg  2xdaily 1 week ago. I am wondering if their is something more I should be doing to help with ttc...vitamins maybe? I am not getting any younger the clock is ticking here. My cycle has always been little to none so is it possible to ovul with out cycle?
Best Answer
Avatar universal
Make sure your doctor monitor's your blood electrolyte levels! Metformin is a wonderful drug BUT can cause DEATH from lactic acidosis...and it is most likely to happen when your first start taking it...make sure your doctor is doing blood tests! Metformin now carries a black box warning from the FDA because of this. Also, keep hard candy with you at all times in case of hypoglycemia. Are you monitoring your blood sugar levels? Metformin is a diabetes drug that lowers blood sugar. It can be used to treat PCOS but it will still affect your blood sugar and hypoglycemia can be dangerous.

That said :)  has your doctor checked your FSH and LH levels? Hubby's sperm count?

http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001408/

Link above to good article on PCOS.

I have friends who swear that red raspberry leaves (usually as a tea) are the best thing to help conception....but I don't have any first hand knowledge.

In answer to your question "My cycle has always been little to none so is it possible to ovul with out cycle?" YES. It is possible to ovulate without having a period.

My cycle has always been irregular except for 3 years when I took Ortho Tri-cyclen for birth control. In fact my oldest child's due date was very hard to determine because I was so irregular (I sometimes went 6 months without a period)...and I had not had a period for a few months when I became pregnant (I think I had my last period with her in July or August 1989...she was born July 1990).

Btw...your dose looks a tad high...what formulation of metformin are you taking? My book says usual dosing is 500mg twice daily to start up to a maximum of 2550mg for regular metformin. Extended release has a lower maximum daily dose.

Be safe and best of luck to you in your quest to conceive (((hug)))

3 Responses
Sort by: Helpful Oldest Newest
Avatar universal
Make sure your doc checks your electrolyte levels (different than FSH and LH). Metformin can be dangerous and you are on a high dose...your doctor MUST watch your blood chemistries (many labs call it a Metabolic Panel...is sodium Na+, potassium K+, chloride Cl+, etc.)

With my pregnancies, I have always felt pregnant. No morning sickness, but fullness in lower abdomen and sudden need to pee every two seconds...so I knew to take a test with my daughter. With my son we were TTC so were testing every month (got BFP 2nd month). With current, I JUST stopped taking birth control and got pregnant that first cycle :)

While it is possible to ovulate without having a period...a lot has to do with why you aren't having a period too. I used to be VERY underweight and didn't have the body fat needed to maintain a normal female cycle (now I am the opposite LOL I have PLENTY of body fat!)...I still have somewhat irregular cycles when not on the pill but usually only skip a month...or have a long cycle...like 45 days.
Helpful - 0
1660049 tn?1326089018
Thanks so much your info has been such an inspiration :} To know that is a possibility of ovul with out cycles.
How did you know of pregnancy? If no cycles?

No my husband has not has his sperm count checked, he has 2 kids from previous.
now that you say that it is possible to tc without cycles bring me to wonder about him.

Doc did check FSH and LH levels.  1000mg of Metformin 2x a day. Makes me feel horrible!  

Thanks for any advice that you have.




Helpful - 0
Have an Answer?

You are reading content posted in the Pregnancy 35 and Older Community

Didn't find the answer you were looking for?
Ask a question
Popular Resources
Get information and tips on how to help you choose the right place to deliver your baby.
Get the facts on how twins and multiples are formed and your chance of carrying more than one baby at a time.
Learn about the risks and benefits of circumcision.
What to expect during the first hours after delivery.
Learn about early screening and test options for your pregnancy.
Learn about testing and treatment for GBS bacterium.