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Proven egg quality and quantity supplements
We have been thru 3 fresh rounds of ivf and an fet. I have had a natural mc at 5 weeks and a D&C at 9 weeks because our little ones heart stopped beating. My DH would like me to try another fresh cycle. I was taking loads of supplements and doing acupuncture these last two fresh cycles. What are the best supplements to take both for quality and quantity? Here is a list of the ones I've been taking. Some of them are for overall health...
N Acetyl cystine 2000
Queens delight (royal jelly)
Coq10 ubiquinol 200mg
Inositol
Omega 3 dha
X FLM K37
Metformin pcos
Neevo DHA prenatal
Folic acid 800mcg
Floridix iron supplement
Vitamin D drops
My acupuncturists isn't a believer in DHEA but has anyone had any great luck with it or anything else.
My DH is really wanting me to try another cycle. He's never asked me this before so I may if I can get a head start on these supplements. I will have a couple months to get them into my system since I have to wait for my lining to build back up nice and strong. Thank you for any help you can offer. We are desperate to have just one baby before we gave to call it quits. You can message me anytime or I will check back here.
Thank you so much for your help!!!
Ginger
N Acetyl cystine 2000
Queens delight (royal jelly)
Coq10 ubiquinol 200mg
Inositol
Omega 3 dha
X FLM K37
Metformin pcos
Neevo DHA prenatal
Folic acid 800mcg
Floridix iron supplement
Vitamin D drops
My acupuncturists isn't a believer in DHEA but has anyone had any great luck with it or anything else.
My DH is really wanting me to try another cycle. He's never asked me this before so I may if I can get a head start on these supplements. I will have a couple months to get them into my system since I have to wait for my lining to build back up nice and strong. Thank you for any help you can offer. We are desperate to have just one baby before we gave to call it quits. You can message me anytime or I will check back here.
Thank you so much for your help!!!
Ginger
Hi,
I was just reading your concerns about costs which I totally understand. We have just switched REs to CNY which offers two fresh IVF cycles including everything except your meds for $6000 with all the subsequent FETs included. That is the only way we are able to do another cycle and just thought you might want to check it out. The PGD is also significantly less at about $2800-3200. Good luck to you!!!!
I was just reading your concerns about costs which I totally understand. We have just switched REs to CNY which offers two fresh IVF cycles including everything except your meds for $6000 with all the subsequent FETs included. That is the only way we are able to do another cycle and just thought you might want to check it out. The PGD is also significantly less at about $2800-3200. Good luck to you!!!!
I was on prednisone and lovenox to prevent blood clots and immun issues which I think got me the furthest I've made it in pregnancy. I'm sure he will do it again if he thinks there is a reason to try again.
If you and your donor had karyotype done then yes they would have known about a balanced translocation. So that should rule that out seeing you guys came back as "normal". If you got new donors, then you would have them tested too.
I had gentic testing done with my miscarriage and my results came back normal for my tissue but inconclusive for the fetus cause the fetus did not grow out to be tested. So I had no answers and was forced to do the reserach myself till I got to the point of comfort. Thats really all you can do, read and get knowledge enough for you to have a comfortable understanding about it all so you can pick yourself up and keep going forward. One thing im sure you know, unless you find a :"specific" issue with youself like blood disorders (like me), progestrone, etc. Gentic issues is all chance and theres never a solution to that issue but strengh to keep trying.
I had gentic testing done with my miscarriage and my results came back normal for my tissue but inconclusive for the fetus cause the fetus did not grow out to be tested. So I had no answers and was forced to do the reserach myself till I got to the point of comfort. Thats really all you can do, read and get knowledge enough for you to have a comfortable understanding about it all so you can pick yourself up and keep going forward. One thing im sure you know, unless you find a :"specific" issue with youself like blood disorders (like me), progestrone, etc. Gentic issues is all chance and theres never a solution to that issue but strengh to keep trying.
Thank you
This is basically what I've read about. The part I wasn't aware of is it usually being the egg quality. The RE went thru a lot of this too the day of surgery but without labels if you will. He knows me too well by now and would know I would be driving myself crazy looking up things. He will share his findings and the solutions for them but not the "what it's". I read if my karyotype was done and normal if it were a female fetus they should be able to know if there was an abnormality it wasn't my tissue since my karyotype is normal. The donors karyotype was normal too. We will have to choose a third donor if we do ivf again so if it were an issue of translocation and they could tell if your a carrier or not then it should show up on the karyotype preformed on me months ago. Is that correct?
My main concern of the odds of having the same trismony repeatedly were answered and you verified them for me. Thank you!
As soon as we consult with the RE I will look into the book as well. I want to know exactly what applies to us and focus on that task and our future treatment if there is any.
This is basically what I've read about. The part I wasn't aware of is it usually being the egg quality. The RE went thru a lot of this too the day of surgery but without labels if you will. He knows me too well by now and would know I would be driving myself crazy looking up things. He will share his findings and the solutions for them but not the "what it's". I read if my karyotype was done and normal if it were a female fetus they should be able to know if there was an abnormality it wasn't my tissue since my karyotype is normal. The donors karyotype was normal too. We will have to choose a third donor if we do ivf again so if it were an issue of translocation and they could tell if your a carrier or not then it should show up on the karyotype preformed on me months ago. Is that correct?
My main concern of the odds of having the same trismony repeatedly were answered and you verified them for me. Thank you!
As soon as we consult with the RE I will look into the book as well. I want to know exactly what applies to us and focus on that task and our future treatment if there is any.
Ginger- I really suggest you getting the book "how to get pregnant" the link is below:
http://www.amazon.com/How-Get-Pregnant-Sherman-Silber/dp/0316066508
This book helped me get an understanding on every level of infertility and how the body works.
From what I know, each chromosonal issue in a miscarriage is usually caused by egg age and division. The division process does not divide properly and thats when chromosones get stuck together causeing trisomy. Trismony "meaning more". Chromosone 21 is the most common cause it is the smallest chromsone and the easiest to stay connected and thats also why some of the times 21 can produce a baby, cause it its the smallest in effect. You can have trismony 15, 18, 21, 7...etc. Sometimes a translocation can take place but usually is casued by a parent having a translocation which is when they have the correct amount of chromsones but 2 of them are connected onto the wrong ones. It will not have effect till you try and have a baby and even then sometimes will not cause issues.
So to answer the question of a gentic issue being the same each time, its unlikey unless its caused but something you or your husband carry. Its usally the eggs guality.
As for the sperm, from what i read, miscarriages that carry out past 6 weeks are most likey not caused by sperm issues, seeing sperm issues are usually when either the head breaks off and doesnt divide causing it to be impossible for life function, and casues a very early miscarriage. Dont get me wrong it is possible for sperm to be the issue but its rare. Usually its issue without the parent being a carrier is turners syndrome, which would mean its a girl. Most cases of turners syndrome is when the x chromsone is missing which is the sperm. when the x chromosne is missing the pregnancy will miscarry.
That also would mean that female fetuses can be testing seeing they do find causes being turners. I hope this helps you somewhat and i really would recommend you gettting this book. This book also helped me threw my miscarriage.
http://www.amazon.com/How-Get-Pregnant-Sherman-Silber/dp/0316066508
This book helped me get an understanding on every level of infertility and how the body works.
From what I know, each chromosonal issue in a miscarriage is usually caused by egg age and division. The division process does not divide properly and thats when chromosones get stuck together causeing trisomy. Trismony "meaning more". Chromosone 21 is the most common cause it is the smallest chromsone and the easiest to stay connected and thats also why some of the times 21 can produce a baby, cause it its the smallest in effect. You can have trismony 15, 18, 21, 7...etc. Sometimes a translocation can take place but usually is casued by a parent having a translocation which is when they have the correct amount of chromsones but 2 of them are connected onto the wrong ones. It will not have effect till you try and have a baby and even then sometimes will not cause issues.
So to answer the question of a gentic issue being the same each time, its unlikey unless its caused but something you or your husband carry. Its usally the eggs guality.
As for the sperm, from what i read, miscarriages that carry out past 6 weeks are most likey not caused by sperm issues, seeing sperm issues are usually when either the head breaks off and doesnt divide causing it to be impossible for life function, and casues a very early miscarriage. Dont get me wrong it is possible for sperm to be the issue but its rare. Usually its issue without the parent being a carrier is turners syndrome, which would mean its a girl. Most cases of turners syndrome is when the x chromsone is missing which is the sperm. when the x chromosne is missing the pregnancy will miscarry.
That also would mean that female fetuses can be testing seeing they do find causes being turners. I hope this helps you somewhat and i really would recommend you gettting this book. This book also helped me threw my miscarriage.
Ginger,
If the tissue is female I guess they are afraid that they got YOUR tissue instead of the embryo. If the tissue is male then it is definitely an embryo and not yours. Therefore, often times when they do genetic analysis (like cvs) and they ask for mother's genetic material to make sure that two samples are different.
If the tissue is female I guess they are afraid that they got YOUR tissue instead of the embryo. If the tissue is male then it is definitely an embryo and not yours. Therefore, often times when they do genetic analysis (like cvs) and they ask for mother's genetic material to make sure that two samples are different.
Ok so this is a little off topic from the original question posted but since I do not know hardly anything about what the meanings of the genetic testing results I read a little. My understanding is that with most of the outcomes are an isolated occurance, is this correct?? If I had several MC's they wouldn't all be for the same reasons? And it was mentioned that if it was a female embryo that chromosome analysis is not possible and they recommend genetic testing for the parent (which I have had and it was fine) so why cant they do a chromosome analysis on a female embryo?? And then like mentioned above we may it ever know why this happened.
So if a single persons MC can vary this greatly how the heck do you pin point the issues to correct the problem? I'm so confused!
Oh and Ecologic I didn't mean to skip your post. I live about 3 hours from the Mexico border but no it wouldn't be something my husband would go for. He only trusts this RE, we've been to so many places before we felt comfortable and so far he hasn't done us wrong, he's been successful with us twice, now I've got to stop loosing these precious babies.
So if a single persons MC can vary this greatly how the heck do you pin point the issues to correct the problem? I'm so confused!
Oh and Ecologic I didn't mean to skip your post. I live about 3 hours from the Mexico border but no it wouldn't be something my husband would go for. He only trusts this RE, we've been to so many places before we felt comfortable and so far he hasn't done us wrong, he's been successful with us twice, now I've got to stop loosing these precious babies.
Yeah we don't do the Lupron protocols. RE likes to do as close to a natural cycle as possible. I wouldn't want to do a Lupron protocol.
I understand how you feel, myfamily is the same way.
Don't let them stop you from achieving your dream though.
By the way, change in ivf protocol can make a difference in terms of quality / quantity you get per cycle. I know that women who switched to protocols w/o Lupron got better results.
Don't let them stop you from achieving your dream though.
By the way, change in ivf protocol can make a difference in terms of quality / quantity you get per cycle. I know that women who switched to protocols w/o Lupron got better results.
I know scar tissue isn't an issue from the major abdominal surgeries I've had but ive read of the increased risk of MC associated with it along with several other risk factors I do have for MC's. That's concerning to me. I know the inside of my uterus is probably the best it can be with the large septum removed and the 4 surgeries total this RE has done in my uterus, he specializes in Ashermans so he's the prefect person to be working in there I think. We have so many different factors honestly I can't organize them well enough to relay here sadly right now my mind is just all over the place.
Donor eggs and embryos are not a problem for myself and probably not a problem with my husband judging by his willingness to use a donor currently but it is a huge issue family wise. Our families have no idea that we even want kids and certainly don't know a thing about these struggles or all these surgeries. It's been hard to hide with most our family living in the same city even. We had a match done with our donor and now he's retired so we will have to start the process over a third time. As far as donor embryos I'm guessing a match isn't going to be possible and donor eggs we simply can't afford. I know this may sound odd but privlidging our families with the information of a donor anything would be really bad. Especially on the child and I need to keep that in mind when making donor decisions. Of course the information would be shared with the child when he/she is old enough to understand but family won't be accepting and could really do emotional damage which I'm not willing to put my future child thru. It's just not fair for someone to grow up feeling bad about themselves as my mom would make sure she would ruin another life.
Donor eggs and embryos are not a problem for myself and probably not a problem with my husband judging by his willingness to use a donor currently but it is a huge issue family wise. Our families have no idea that we even want kids and certainly don't know a thing about these struggles or all these surgeries. It's been hard to hide with most our family living in the same city even. We had a match done with our donor and now he's retired so we will have to start the process over a third time. As far as donor embryos I'm guessing a match isn't going to be possible and donor eggs we simply can't afford. I know this may sound odd but privlidging our families with the information of a donor anything would be really bad. Especially on the child and I need to keep that in mind when making donor decisions. Of course the information would be shared with the child when he/she is old enough to understand but family won't be accepting and could really do emotional damage which I'm not willing to put my future child thru. It's just not fair for someone to grow up feeling bad about themselves as my mom would make sure she would ruin another life.
Have you considered going to Mexico for IVF? I saw a reportage once and it was very impressive, they have IVF clinics that target Americans and Canadians for 1/3 of the price - with donor eggs.
Good luck, you're in a dark period now but stay hopefull!
Good luck, you're in a dark period now but stay hopefull!
Ginger, since you are using a donor for sperm already, why not try donor embryos instead of donor eggs? It is less invasive and you don't have to pay for egg donor.
In the US I am pretty sure they test all chromosomes (a friend of mine had a m/c due to trisomy of chromosome 6 as it turned out after the lab testing) but since you actually saw a h/b I doubt lab testing will provide you with much more info. Surgeries and scar tissue are not a factory with ivf; I have severe scar tissue from multiple prior surgeries. I think adgal is right, you just have to try again. You came sooo close this time!
I wish you all the luck in the world.
In the US I am pretty sure they test all chromosomes (a friend of mine had a m/c due to trisomy of chromosome 6 as it turned out after the lab testing) but since you actually saw a h/b I doubt lab testing will provide you with much more info. Surgeries and scar tissue are not a factory with ivf; I have severe scar tissue from multiple prior surgeries. I think adgal is right, you just have to try again. You came sooo close this time!
I wish you all the luck in the world.
Thank you all for your opinions. I understand that there are different opinions and that's exactly why I posted this question.
There are so many factors in our case, too lengthy to list here Properly so you got the full picture. I've had tons of testing 6 gyn surgeries and three ER's. 14 surgeries total by age 37. I feel like a lab rat. DH has severe factors too and we have to use a donor so some of the more specialized testing on the donors part is obviously out of reach. We will have genetIc testing results in a couple weeks along with the consult with the RE, his colleagues and the embryologist. I'm on meds for a couple months anyways. DH wants me to try again and I dont want to go thru another loss. Im not being negative just realistic. I know donor eggs are going to be brought up which I don't have a problem with except we won't be able to afford them after all the money spent. I have one last round of ivf paid for and has to be used by a certain time. If I wanted to purchase more Pre paid cycles I would have to have the paperwork in in a few months or I will be denied because of my age.
Thank you everyone for your opinions and sharing your research.
Best wishes to everyone wherever your at on this roller coaster ride.
There are so many factors in our case, too lengthy to list here Properly so you got the full picture. I've had tons of testing 6 gyn surgeries and three ER's. 14 surgeries total by age 37. I feel like a lab rat. DH has severe factors too and we have to use a donor so some of the more specialized testing on the donors part is obviously out of reach. We will have genetIc testing results in a couple weeks along with the consult with the RE, his colleagues and the embryologist. I'm on meds for a couple months anyways. DH wants me to try again and I dont want to go thru another loss. Im not being negative just realistic. I know donor eggs are going to be brought up which I don't have a problem with except we won't be able to afford them after all the money spent. I have one last round of ivf paid for and has to be used by a certain time. If I wanted to purchase more Pre paid cycles I would have to have the paperwork in in a few months or I will be denied because of my age.
Thank you everyone for your opinions and sharing your research.
Best wishes to everyone wherever your at on this roller coaster ride.
I am so incredibly sorry for what you have been through. I've also had several miscarriages and I so understand your heartbreak. I got lucky with pregnancy no. 6 at 40, so do not give up hope. Since then I have miscarried 3 more times, and in our case have decided to move forward with embryo adoption (not the right decision for all, just the right decision for us). I have now had pretty much every test under the sun in my RE's (and prior to that my OB's) attempt to discover why this kept happening. I would like to share some of that with you in hopes that perhaps it may help.
I had 4 d&c's. In each of those cases, plus 1 of my natural losses the fetal tissue was tested. There were no chromosomnal abnormalities found. I probed further in my questioning and discovered that they really only test for the 3 most common....trisonomy 13, 18 and 21. So the fact that nothing was found cannot truly exclude an abnormality, it just wasn't one of the one's tested for. We underwent testing for genetic incompatability (rare, but it happens). Again, nothing. They have looked at my uterus from every possible angle - as I said, you name it, I've had it. It truly is still a mystery. The reality is that a lot of the time they just don't find anything. It's just a combination of age and bad luck. And my opinion is that of Helen's....I just do not believe there is a thing that can be done about it. I don't mean to be a downer, it's just what my own personal search for answers has taught me. I also mean no disrespect to the opinions of others.
If I were in your shoes (and I have been), here is what I would do. I would await all test results. A few more months won't hurt anything. Once you have all the information in hand, I would take that and make a decision from there. In your situation, an alternative might well prove to be the answer. Again, please do not take my response as a negative - I just want to see your dream fulfilled as I know very well how much pain you are probably in right now.
Again, I'm so sorry, and I wish you nothing but success in your journey.
I had 4 d&c's. In each of those cases, plus 1 of my natural losses the fetal tissue was tested. There were no chromosomnal abnormalities found. I probed further in my questioning and discovered that they really only test for the 3 most common....trisonomy 13, 18 and 21. So the fact that nothing was found cannot truly exclude an abnormality, it just wasn't one of the one's tested for. We underwent testing for genetic incompatability (rare, but it happens). Again, nothing. They have looked at my uterus from every possible angle - as I said, you name it, I've had it. It truly is still a mystery. The reality is that a lot of the time they just don't find anything. It's just a combination of age and bad luck. And my opinion is that of Helen's....I just do not believe there is a thing that can be done about it. I don't mean to be a downer, it's just what my own personal search for answers has taught me. I also mean no disrespect to the opinions of others.
If I were in your shoes (and I have been), here is what I would do. I would await all test results. A few more months won't hurt anything. Once you have all the information in hand, I would take that and make a decision from there. In your situation, an alternative might well prove to be the answer. Again, please do not take my response as a negative - I just want to see your dream fulfilled as I know very well how much pain you are probably in right now.
Again, I'm so sorry, and I wish you nothing but success in your journey.
and I disagree with helen I think with certain suppliments eg, maca, inositol, royal jelly etc you can def improve egg health otherwise ivf doctors wouldnt put ladies on them !!
Oh and now I've broken out in a rash with the cordyceps all over my face!! My acupuncturist wants me on it along with wheatgrass
Thanks Helen
I know we are born with a set amount and all that. When I wasn't on all the supplements nothing happened. If its not helping the egg quality per say it's at least helping my overall health. I've been a sickly person even as a baby. I know im lucky to produce 20-21 eggs consistently at my age. Some ladies only have 5 or so. I could produce 100 and if they are no good they are useless. I am at the end of a journey I've spent 20 yrs to get to and reality is setting in that there is a great chance that it's not going to happen for us.
We will either know more with the pathology or be just as clueless as we are now.
I know we are born with a set amount and all that. When I wasn't on all the supplements nothing happened. If its not helping the egg quality per say it's at least helping my overall health. I've been a sickly person even as a baby. I know im lucky to produce 20-21 eggs consistently at my age. Some ladies only have 5 or so. I could produce 100 and if they are no good they are useless. I am at the end of a journey I've spent 20 yrs to get to and reality is setting in that there is a great chance that it's not going to happen for us.
We will either know more with the pathology or be just as clueless as we are now.
Ginger, I love you my friend but egg quantity and quality cannot be changed with ANY supplement. Every woman is born with a finate number of eggs. Unlike men who produce sperm, women do not actually produce eggs. We are born with a limited amount and we release them one per cycle, typically. As a woman approaches the end of her ovarian reserve, both quantity and quality decline. When a woman is out of eggs, she enter menopause. Unfortunately, we can't change the date when we run out of eggs since the number is fixed at birth. I know you want to improve your chances but human biology just does not work that way. The fact that you got pregnant twice before is a good sign. All you need is one sticky embryo.
(Hugs)
(Hugs)
We both have many fertility factors but his make it completely impossible for natural conception.
Do you have blocked tubes or your partner has low sperm count?
I suffered from unexplained infertility for 2 full years, lost ovary function on one side as well (ovarian cyst). We did an IVF: miscarriage. Then I started to get pregnant naturally, a few more miscarriages and then a successfull pregnancy.
Unexpected things can happen sometimes! Good luck!
I suffered from unexplained infertility for 2 full years, lost ovary function on one side as well (ovarian cyst). We did an IVF: miscarriage. Then I started to get pregnant naturally, a few more miscarriages and then a successfull pregnancy.
Unexpected things can happen sometimes! Good luck!
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