I left mine in the whole time with my first and it stretched it to where my top hole had stretch marks coming from it and the skin that held it in was stretched too thin. I even tried a "pregnancy belly ring" and it didn't work. I took it out this time. I'd say best bet is to take it out. But that's your choice.
I left one in my entire pregnancy last time... However I bought a pregnancy belly ring that isflexible and you cut it to size when my stomach grew it all depends on what's comfortable to you