Pregnancy Expert Forum
Clexane during pregnancy
About This Forum:

This forum is for questions and support regarding Caesarean Section , Childbirth, Diabetes, Depression, Fetal Monitoring, Genetic Testing, Hormonal Changes, Labor, Lamaze, Morning Sickness , Nutrition, Parenting, Prenatal Care, Weight gain.

Font Size:
A
A
A
Background:
Blank
Blank
Blank
This expert forum is not accepting new questions. Please post your question in one of our medical support communities.
Blank Blank

Clexane during pregnancy

I made some genetic testing and the results are:
protrombin mutation heterozygote, MTHFR A1298C homozygote and B fibrinogen heterozygote. Factor V is normal. Antithrombin III normal. Antiphospholipide antibodies negative.
Now I`m 37 weeks pregnant and on therapy with Clexane 20 mg the last 2 weeks before that (until 30 week of pregnancy) I was taking baby aspirin. I have history of two miscarriages.
I want to ask you, should I take this medication till labor begins? After delivery should I continue with the therapy (for prevention of thrombosis)? What is your therapy in cases like mine - thrombophilia? Can you tell me what do you prescript from the begining till the end of the pregnancy with thrombophillia?
Thank you very much.
Related Discussions
242596_tn?1192429549
Hello,

There is some variety in how anticoagulants are used during pregnancy for women who have risk factors for clotting.  Most women in this setting are being managed or have been consulted on by a high risk obstetrician which I am not (I am a general ob/gyn).  That said, many of my MFM colleagues would argue in the absence of ever having a clot (if that indeed is the case) to continue a baby aspirin only.  When Clexane (or enoxaprin, low molecular weight heparin) is initiated we usually switch women to unfractionated heparin at 36 weeks given the uncertaintly of the onset of labor in order to minimize the risk of excessive bleeding or make a spinal or epidural too risky.  

In terms of the duration of use after delivery, this is usually guided by one's thromboembolic history (that is to say, if they have had a clot or not) and mode of delivery (cesarean vs. vaginal).  In your case some might suggest you could stop after a vaginal delivery, others, more conservatively, may suggest to continue until six weeks postpartum, regardless of mode of delivery.  

If you have concerns about how you are being managed I suggest you seek a formal second opinion.

Best regards,

Dr. Downing
2 Comments
Blank
Avatar_f_tn
I had my first IUI procedure on June 10. All my test came up great, HCG, Blood work, Clomid is working. I am very ansioux to know if it worked. My doctor said I had to wait 17-days after which will be June 26, if my mensus dont come then I just call and come in for a Blood PG test, very anxious and nervous. For the past 4-days I have charted my temp and its been the same 97.4, 97.6, 97.4 & 97.9 does that necessary mean anything? Is that a good for bad sign? Can anyone relate and give me some sort of advice, my doctor advised me not to take a PG test at home just wait for the blood.. THanks
Blank
Avatar_f_tn
A related discussion, Clexane was started.
Blank
Continue discussion Blank
This Forum's Experts
603463_tn?1220630455
Elaine Brown, MDBlank
Elaine Brown, MD - BLOG
Billings, MT
MedHelp Health Answers
Blank
Weight Tracker
Weight Tracker
Start Tracking Now
RSS Expert Activity
233488_tn?1310696703
Blank
New Cannabis Article from NORTH Mag...
Jul 20 by John C Hagan III, MD, FACS, FAAOBlank
242532_tn?1269553979
Blank
3 Reasons Why You are Still Binge E...
Jul 14 by Roger Gould, M.D.Blank
242532_tn?1269553979
Blank
Emotional Eating: What Your Closet ...
Jul 09 by Roger Gould, M.D.Blank