This forum is for questions and support regarding Caesarean Section , Childbirth, Diabetes, Depression, Fetal Monitoring, Genetic Testing, Hormonal Changes, Labor, Lamaze, Morning Sickness , Nutrition, Parenting, Prenatal Care, Weight gain.
I am on long term Nexium (40 mg/twice daily) and Amitriptylin (25 mg/once daily) with Ativan (0.5 mg) only when necessary for Nausea.
I just recently realized that I am 7 weeks pregnant, something that was unplanned and unexpected since I had problems with ovulation and was under the impression that pregnancy could only occur with ovarian stimulation or specialized intervention.
In any case I was for the duration of pregnancy taking Amitriptylin once daily and took several Lorazepam tablets (10-15) for Nausea which I thought was my usual Nausea that I always complain from and later turned out to be due to pregnancy. Upon my research I found out that the Amitriptylin is a category C drug and Lorazepam is a category D, both that are unsafe during pregnancy. My OB is researching if we need to terminate this pregnancy. However, I would like to know your medical opinion as well to feel more comfortable.
As you are aware, each of the drugs you described carries some risk to the fetus.
A drug in the C category should be used only if the benefit outweighs the risk, and in the D category has shown some actual evidence of harm. From what I can discover, the biggest risk with Lorezepam is the risk to the baby of addiction and withdrawl (withdrawal) syndrome.
Obviously, if you discontinue the medication now that won't be an issue. The other potential problem is an increased risk of cleft lip and palate associated with its use.
Cleft lip can be ruled in or out by a targeted ultrasound, and is repairable if it occurs.
You are really the only one who can determine whether the risk is high enough for you to consider termination. Obviously there are other factors that go into making that decision.
If you were my patient, I would advise you to discontinue the medications and I would offer you the option of genetic testing and targeted ultrasound. If you elected to terminate the pregnancy, I would not be judgemental. Because the risk of birth defects is so small however, I would not recommend termination based only on your exposure.
I hope this is useful and helpful!
Copyright 1994-2016 MedHelp International. All rights reserved.
MedHelp is a division of Aptus Health.
This site complies with the HONcode standard for trustworthy health information.
The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. Med Help International, Inc. is not a medical or healthcare provider and your use of this Site does not create a doctor / patient relationship. We disclaim all responsibility for the professional qualifications and licensing of, and services provided by, any physician or other health providers posting on or otherwise referred to on this Site and/or any Third Party Site. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. We offer this Site AS IS and without any warranties. By using this Site you agree to the following Terms and Conditions. If you think you may have a medical emergency, call your physician or 911 immediately.