HeinrikMD regarding question

[runnerdavid]

I have a question for the Doctor.  I had an elevated PSA reading of 4.43 in 10/2010.  My last readings were in 2007/2008 in same months Oct.  they were 2.64 &  2.62.  In Oct 2010 my Doctor performed DRE and felt nothing and requested a biospy.  I had a 16 core biopsy performed in Nov 2010 all clear except one was abnormal (ASAP).  Doctor recomended another 16 core biopsy in January 6, 2011.  All cores were normal.  My question is what questions should I ask my Doctor when I see him in april 5  2011.   I have been under quite intense amount of depression and anxiety for the last several months regarding the prostate evaluation.   Thanks for any and all help.  

[runnerdavid]

Hello and thank you for your comments. I am 56 years old and I am having a meeting with a urologist tonight for a second opinion.  I am uneasy with my current urologist and this is why I am seeking the second opinion.  You mention a factor which leads to  biopsies is when a nodule or surface variation is detected which was not the case with me.  My Doctor told me he did not feel anything,  other than having an elevated PSA?

[geriatric456]

You do not give your age which is very relevant to your PSA readings. Preumably you are not on any medication.  As your last biopsy was clear I doubt if your Doctor would recommend an other one but would monitor your PSA every six months.
PSA readings are unfortunately only a guide and can be increased by various factors and lead to many unnecessary biopsies whish are not without risk.
Usually a nodule or surface variation  detected by either DRE or TRUS would be present before requesting a biopsy.
It is not abnormal to feel anxiety and depression in your situation but from what you have said it does seem that you are OK.  Have you confidence in your Doctor's evaluation of your situation?