Looking for Opinions regarding high PSA biobsy etc

[kimo_ie_jim]

I am a 63 year old man in good health. I exercise daily using a combination of walking, biking yoga and light weights. I eat a very health diet and people tell me I look as if I am years younger, Dr's have said the same. I am of average weight. I started monitoring my psa years ago and it has slowly risen over time. My prostate is swollen and I urinate slowly particularly at night. I have been taking a saw pawmento complex for years. Dr's have not felt anything abnormal besides the swelling on palpation. I have an active sex life which I enjoy.

Recent PSa
03/29/2011 Total 17.2 NG/ML no free done **
02/20/2006 Total 12.5 MG/ML Free 2.10 % Free PSA 17% lab results state about 20% chance of cancer*
9/21/2010 Total 13.3NG/ML Free 3.23 NG/ML % free 24% lab results state about 16% chance of cancer*

*Test Performed by: Beckman/Coulter access Chemilumineescent Assay
**Test performed by: Siemens Centaur Chemi luminescent Assay

I had a biopsy of the prostate in June of 2005
12 samples were taken
3 sites showed Benign prostate Tissue
2 sites showed Benign prostate tissue, with rare involuted glands
1 site showed Benign prostate tissue, showing focal involutional change
2 sites showed Benign prostate tissue showing prominent involutional change
1 site showed benign chronically inflamed prostate tissue
1 site showed benign prostate & hypertrophied stroma
1 site showed benign prostate & stromal tissue
1 site showed Focal high-grade prostatic intraepithelial neoplasia (HGPIN)

As a result of the recent psa total 17.2 NG/ML my Urologist is recommending another biopsies with 18 samples taken. He also stated that there is about a 35% chance that I have cancer but if it comes up negative he wants to put me on Avodent administered once a week.

I am wondering what if you would offer any suggestions or advice, I thank you in advance for you assistance.

[curmudgen]

I recommend this book for all to read...balance approach -- written by a doctor and co-author with PV

"Invasion of the Prostate Snatchers: No More Unnecessary Biopsies, Radical Treatment or Loss of Sexual Potency"

[WTL]

Forgot to say that I think your doctor is right on track and that you should have a biopsy. It's a drag - I know, I've had several, going to have another in a couple of weeks. But the annoyance passes and the knowledge gained can save your life. So my advice is to listen to your doctor. The more samples the better - my last one had 24.

[WTL]

I'm on my third bout with PC - not a doctor, just read a lot and ask questions, so my response here is entirely amateur. 17.2 is a pretty high PSA to not have cancer - but it's entirely possible that your BPH and inflammation alone is causing it. My doctor makes me abstain from sex for a week before testing - you probably know sex raises your PSA for a couple of days afterward. That high-grade PIN is definitely associated with PC at that 35%-rate your doctor mentioned - and still that's a minority of cases, and your free PSA is comforting, but the longer it's been since your biopsy the greater the chance that cancer has developed. This is a good site for all PC matters: http://www.prostate-cancer.org, and this is what the site has to say about PIN: http://www.prostate-cancer.org/education/preclin/pin.html