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PSA level rising

by virtual, Sep 17, 2009 11:52AM
Dear doctor,
I am writing on behalf of my colleague who was diagnosed with prostatic cancer in 2002. A total prostatectomy and radiotherapy were performed.
It all went well and he got back to work (he is a psychiatrist).
In the following years, the PSA level started to grow, and three PET – CT scans were performed.
The last one was in June 2008., without any pathological finding.
However, at the same time the PSA was 1.84, so his doctor suggested starting a treatment with Casodex which he was using for a year (dosage 150 mg per day).
He had side-effects such as gynecomastia, but otherwise tolerated the drug well and was working the whole time.
The PSA level slowly started to decrease up to 0.1777.
Less than a month ago, the treatment with Casodex was stopped and yesterday he got the PSA results.
It was rather high again  – 0.905.

Could you please tell us what this might mean?
He feels great, all other tests are normal, besides this PSA which is slowly increasing again.
What would be the best thing to do at this point?

Sincerely,
NNV.
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