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folic acid metabolism
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folic acid metabolism

74 yr old man, CAT scan normal, prostate normal, BP 120/60, blood panels normal but has always had anemia (below "normal" on scale).  Dr. prescribed folic acid at last physical exam -(1 mg. cheap little yellow pills).  This "anemia" runs in the family.  Has been taking folic acid for 2 months and now takes vitamin pill and ensure, both of which contain more folic acid.  He developed rash,  and has deteriorated severely.  He has lost 25 lbs and is now down to 160 lbs., he has lost his sense of taste and has a metallic taste in his mouth, he has no appetite, he is so weak he can't run, he sleeps most of the day, he has night sweats, changing p.j.s 3-4 times a night, he feels horrible.  In the middle of all this, his rib broke for no apparent reason.   The Dr., an internist, has no clue as to what's going on.  I am concerned that he is suffering from folic acid poisoning, due to an inability to metabolize the form he's taking. Do you agree or think something else is going on?  He has stopped taking folic acid until he finds out.
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selmaS
Allentown, PA