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macrocytosis with high B12 levels

by Jehoshophat, May 20, 2009 10:18PM
I have macrocytosis and my serum B12/folate levels are normal to high.  However, I am showing signs of B12 deficiency with numbness in my hands and feet and pain in my legs.  Is it possible to have a B12 deficiency and still have normal to high serum levels of B12?
Member Comments (2)

by Dr_Veena, May 22, 2009 11:38AM
Hi,
      Thanks for writing in. Macrocytosis is a symptom of B12 deficiency, folic acid deficiency, liver disease, alcoholism, chemotherapy, increased red cell production in the bone marrow etc.
Numbness in the upper and lower limbs could be due to peripheral vascular disease, stroke, radiculopathy, migraine, whiplash injury etc.
I would suggest that you visit a physician for work up on this and for further confirmation of diagnosis.
Best.

by sting123456, Jun 02, 2009 07:51PM
To: Jehoshophat
When you say normal to high, what is the exact number when you got tested?

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