neuromuscular or metabolic diseases

is adrenoleukodystrophy a neuro muscular or metabolic disease?

[Dr Santos]

Hi,
How are you? Adrenoleukodystrophy is a rare inherited metabolic disorder.wherein the fatty covering (myelin sheath) on nerve fibers in the brain is lost, and the adrenal gland degenerates, leading to progressive neurological disability and death. This is the medical condition in the movie "Lorenzo's oil" which was shown in 1993.

[mixedblessings]

thank you very much for your response. is it possible for my brother and my son to also have this? my brother has gone through practily ever infection i have and his cns is now involved as well. my son is a carbon copy of me for battling infections and his heart is now involved. my brother is 43 and my son is 20.
thank you
mixedblessings

[Dr Santos]

Hi,
As mentioned, adrenoleukodystrophy is passed down from parents to their children as an X-linked genetic trait. It therefore affects mostly males, although some women who are carriers can have milder forms of the disease. There are three major categories of disease including childhood cerebral form, adrenomyelopathy ( occurs in men in their 20s or later in life) and impaired adrenal gland function (called Addison disease or Addison-like phenotype). Chromosome study to look for changes (mutations) in the ABCD1 gene or MRI of the head of your brother or son can help. Take care always.

[sickofsick62]

PLRASE TELL NE WHAY TO LOOK FOR IN MY BLOODWORK,FOTGIVE ERRORS AS MY VISION IS BLURRY

[Dr Santos]

Hi,
How are you? Can you elaborate on what blood work and symptoms you are experiencing? Were you able to have your vision checked by your eye doctor? I really want to help and hope to hear from you soon.