Years ago I was actually a patient at your hospital, and I just got the regular treatment. I look back on everything and basically I realized that is all they really did was a bunch of tests other than give me medications. So anyways I've done a bunch of studying and such on biochemical disorders and asthma and such. I had some IgE test ran a while back and they were completely normal. This would give evidence that my asthma isnt allergy induced. So I was thinking that its a metabolic disorder of some sort. So I was just wondering, what are some metabolic disorders that cause asthma like reactions? The only one that I can think of is a sulfite disorder, but I dont really fit the full spectrum of a sulfite disorder.
Asthma can be caused by both allergic and nonallergic causes. This does not imply that there is ANY metabolic disorder that is the cause of the asthma. There are many adults and children with this problem. Basically it is treated in the same manner as those with allergic asthma, except there is no emphasis on treating or avoiding allergens. The medicines are the same. Those with nonallergic asthma, who develop this problem as adults, in some cases, have a somewhat more severe course, but this is not the case for everyone. The triggers for these attacks can be irritant exposure, sensitivity to aspirin products, infections etc. Chronic sinusitis is a fairly common problem, as well, as a trigger of chronic asthma problems. I would work with your doctor to try to identify the common triggers of your symptoms. Please read about what makes asthma worse at http://www.nationaljewish.org/disease-info/diseases/asthma/about/worse/index.aspx for more detailed information identifying your triggers and minimizing your exposure to them.
Hospitals are places where you get medications and testing. Were you expecting something different? Just curious...
A line from this page:
"[In children]In contrast, serum IgE levels in those with respiratory allergies but no atopic dermatitis are only moderately elevated or even occasionally within normal limits."
Also, don't forget that IgE levels will vary. The one level you had done is only a snapshot. The above article admits that pulmonologists underutilize this test. The levels could vary depending on the state of your breathing.
I believe that exercise-induced asthma is a fairly common occurrence.
Ok, well, I do have eczema, but I really dont think that this is allergies. My eczema gets worse when I sweat, giving reason that there is something that my body has in access that is being released in sweat, maybe something acidic? The Doctors have listened to my lungs, and done the breathing test, its all normal, technically I dont have asthma. I probably should have expected that you would have said the testing is done at hospitals, but I dont know what to get tested for, thats why I was wondering what metabolic disorders are associated with eczema and asthma?
Acid-base disturbances in acute asthma
CHEST, Sept, 1990 by Richard D. Mountain, John E. Heffner, Newton C. Brackett, Jr., Steven A. Sahn
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The typical arterial blood gas and acid-base profile in acute asthma is hypoxemia, hypocapnia, and respiratory alkalosis. (1) Metabolic acidosis in adults with acute asthma is thought to be uncommon (2): however, when acute asthma is severe, metabolic acidosis may occur. (3,4) We examined the clinical features, arterial blood gases, and acid-base profile in 229 consecutive episodes of acute asthma in 170 patients who required hospitalization and found that metabolic acidosis with and without an increase in the anion gap occurred in 28.0 percent of these episodes. Patients with metabolic acidosis were more hypoxemic and had evidence of greater airflow obstruction compared with those without metabolic acidosis. It appears that the metabolic acidosis of acute asthma is due primarily to lactic acidosis caused by a variable contribution of lactate production by respiratory muscles, tissue hypoxia, and intracellular alkalosis; the nonanion gap metabolic acidosis of acute asthma most likely represents a metabolic acidosis superimposed on the tendency to hyperchloremia seen with hyperventilation.
Metabolic acidosis is a snapshot of your blood gases. When lung diffusion becomes normal, your blood gases will revert to normal.
Eczema is a HUGE symptom of allergies. A childhood friend who was a severe asthmatic had severe eczema throughout her childhood. A friend's son, who has severe food allergies (that have abated somewhat now that he's a teenager) had terrible problems with eczema when he was a child.
Here's a great page from a pathologist's point of view on lung disease, although nothing specifically for asthma.
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